Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes
Objective This study aims to explore the current cognitive status and identify risk factors associated with cognitive function in Tibetan hypertensive patients living at various altitudes.Methods The Simple Mental Status Scale (MMSE) was used to evaluate the cognitive function of 611 Tibetan hyperte...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
|
| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/10641963.2024.2393331 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850065124746854400 |
|---|---|
| author | Long Yin Xiaoming Zhang Huijuan Zhang Ruizhen Li Jing Zeng Kaixuan Dong Yi Wang Xinghui Li |
| author_facet | Long Yin Xiaoming Zhang Huijuan Zhang Ruizhen Li Jing Zeng Kaixuan Dong Yi Wang Xinghui Li |
| author_sort | Long Yin |
| collection | DOAJ |
| description | Objective This study aims to explore the current cognitive status and identify risk factors associated with cognitive function in Tibetan hypertensive patients living at various altitudes.Methods The Simple Mental Status Scale (MMSE) was used to evaluate the cognitive function of 611 Tibetan hypertensive patients at various altitudes in Gannan Tibetan Autonomous Prefecture. Afterward, we conducted an analysis to identify the factors influencing their cognitive function.Results The study found that the prevalence of cognitive dysfunction was 22.3%, with a higher incidence at high altitude (group D 29.0%) compared to low altitude (group A 16.0%). The study conducted a binary logistic regression analysis to identify the risk factors for cognitive dysfunction. The analysis revealed that altitude, age, body mass index, marital status, education, income level, and blood pressure control level were all significant risk factors. After controlling for age, body mass index, marital status, educational level, income level, and blood pressure control level, the risk of developing cognitive dysfunction was 2.773 times higher (p < .05) for individuals in group C at high altitude and 2.381 times higher (p < .05) for individuals in group D at high altitude compared to those in group A at low altitude.Conclusions Altitude plays a role in the development of cognitive dysfunction in hypertensive patients. Tibetan hypertensive patients living at high altitudes may be at a higher risk of cognitive dysfunction compared to those living at lower altitudes. Therefore, interventions should be targeted to prevent or mitigate potential cognitive impairment. |
| format | Article |
| id | doaj-art-8fa7bcdf278d4f4296cedba405a56e98 |
| institution | DOAJ |
| issn | 1064-1963 1525-6006 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj-art-8fa7bcdf278d4f4296cedba405a56e982025-08-20T02:49:05ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062024-12-0146110.1080/10641963.2024.2393331Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudesLong Yin0Xiaoming Zhang1Huijuan Zhang2Ruizhen Li3Jing Zeng4Kaixuan Dong5Yi Wang6Xinghui Li7The First Clinical Medical College, Lanzhou University, Lanzhou, ChinaDepartment of Cardiology, Gansu Provincial Hospital, Lanzhou, ChinaDepartment of Cardiology, Gansu Provincial Hospital, Lanzhou, ChinaDepartment of Cardiology, Gansu Provincial Hospital, Lanzhou, ChinaDepartment of Cardiology, Gansu Provincial Hospital, Lanzhou, ChinaThe First Clinical Medical College, Lanzhou University, Lanzhou, ChinaThe First Clinical Medical College, Lanzhou University, Lanzhou, ChinaThe First Clinical Medical College, Lanzhou University, Lanzhou, ChinaObjective This study aims to explore the current cognitive status and identify risk factors associated with cognitive function in Tibetan hypertensive patients living at various altitudes.Methods The Simple Mental Status Scale (MMSE) was used to evaluate the cognitive function of 611 Tibetan hypertensive patients at various altitudes in Gannan Tibetan Autonomous Prefecture. Afterward, we conducted an analysis to identify the factors influencing their cognitive function.Results The study found that the prevalence of cognitive dysfunction was 22.3%, with a higher incidence at high altitude (group D 29.0%) compared to low altitude (group A 16.0%). The study conducted a binary logistic regression analysis to identify the risk factors for cognitive dysfunction. The analysis revealed that altitude, age, body mass index, marital status, education, income level, and blood pressure control level were all significant risk factors. After controlling for age, body mass index, marital status, educational level, income level, and blood pressure control level, the risk of developing cognitive dysfunction was 2.773 times higher (p < .05) for individuals in group C at high altitude and 2.381 times higher (p < .05) for individuals in group D at high altitude compared to those in group A at low altitude.Conclusions Altitude plays a role in the development of cognitive dysfunction in hypertensive patients. Tibetan hypertensive patients living at high altitudes may be at a higher risk of cognitive dysfunction compared to those living at lower altitudes. Therefore, interventions should be targeted to prevent or mitigate potential cognitive impairment.https://www.tandfonline.com/doi/10.1080/10641963.2024.2393331AltitudesTibetanshypertensioncognitive dysfunctionMMSE |
| spellingShingle | Long Yin Xiaoming Zhang Huijuan Zhang Ruizhen Li Jing Zeng Kaixuan Dong Yi Wang Xinghui Li Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes Clinical and Experimental Hypertension Altitudes Tibetans hypertension cognitive dysfunction MMSE |
| title | Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes |
| title_full | Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes |
| title_fullStr | Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes |
| title_full_unstemmed | Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes |
| title_short | Analysis of the current status and associated risk factors of cognitive function in Tibetan hypertensive patients at various altitudes |
| title_sort | analysis of the current status and associated risk factors of cognitive function in tibetan hypertensive patients at various altitudes |
| topic | Altitudes Tibetans hypertension cognitive dysfunction MMSE |
| url | https://www.tandfonline.com/doi/10.1080/10641963.2024.2393331 |
| work_keys_str_mv | AT longyin analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT xiaomingzhang analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT huijuanzhang analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT ruizhenli analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT jingzeng analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT kaixuandong analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT yiwang analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes AT xinghuili analysisofthecurrentstatusandassociatedriskfactorsofcognitivefunctionintibetanhypertensivepatientsatvariousaltitudes |