Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males

Background: Androgenetic alopecia is the most common form of hair loss in men, characterized by progressive thinning of scalp hair. Several factors have been implicated in its pathogenesis, including smoking, which induces oxidative stress that potentially affects the hair follicle health. The stud...

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Main Authors: Nasira Nasr, Umaima Afzal, Karishma Mushtaq
Format: Article
Language:English
Published: ziauddin University 2025-07-01
Series:Pakistan Journal of Medicine and Dentistry
Subjects:
Online Access:https://ojs.zu.edu.pk/pjmd/article/view/3837
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author Nasira Nasr
Umaima Afzal
Karishma Mushtaq
author_facet Nasira Nasr
Umaima Afzal
Karishma Mushtaq
author_sort Nasira Nasr
collection DOAJ
description Background: Androgenetic alopecia is the most common form of hair loss in men, characterized by progressive thinning of scalp hair. Several factors have been implicated in its pathogenesis, including smoking, which induces oxidative stress that potentially affects the hair follicle health. The study aims to evaluate the association between smoking and the presence and severity of androgenetic alopecia in adult males. Methods: A cross-sectional study was conducted at the Combined Military Hospital, Rawalakot, for 6 months from July 2024 to December 2024. The inclusion criteria comprised adult males aged 18 to 50 years with a clinical diagnosis of androgenetic alopecia, who were willing to provide informed consent, including both smokers and non-smokers. Data were collected using a structured questionnaire. Smoking status was categorized as current, former, or non-smoker. Clinical assessment of AGA was performed by a dermatologist using the Hamilton-Norwood scale. Statistical analysis was done using SPSS 26, the chi-square test, with significance at p < 0.05. Results: Among the 120 participants, 84 (70%) had androgenetic alopecia. A significant association was observed between smoking status and the presence of AGA (p < 0.0001). Furthermore, the severity of AGA was significantly higher among current smokers compared to non-smokers (p = 0.017). Conclusion: There is a substantial correlation between smoking and the degree and presence of androgenetic alopecia. These results underline the significance of quitting smoking at an early age and suggest that smoking may be a modifiable risk factor in the development of AGA.
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spelling doaj-art-8fa784b64e334d9480e956570e6ffb212025-08-20T02:41:20Zengziauddin UniversityPakistan Journal of Medicine and Dentistry2313-73712308-25932025-07-0114310.36283/ziun-pjmd14-3/054Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult MalesNasira Nasr0Umaima Afzal 1Karishma Mushtaq 2Poonch Medical College/ Combined Military Hospital Rawalakot,Pakistan.Dr Kashif's Aesthetic Studio,Pakistan.Pak Emirates Military Hospital Rawalpindi,Pakistan. Background: Androgenetic alopecia is the most common form of hair loss in men, characterized by progressive thinning of scalp hair. Several factors have been implicated in its pathogenesis, including smoking, which induces oxidative stress that potentially affects the hair follicle health. The study aims to evaluate the association between smoking and the presence and severity of androgenetic alopecia in adult males. Methods: A cross-sectional study was conducted at the Combined Military Hospital, Rawalakot, for 6 months from July 2024 to December 2024. The inclusion criteria comprised adult males aged 18 to 50 years with a clinical diagnosis of androgenetic alopecia, who were willing to provide informed consent, including both smokers and non-smokers. Data were collected using a structured questionnaire. Smoking status was categorized as current, former, or non-smoker. Clinical assessment of AGA was performed by a dermatologist using the Hamilton-Norwood scale. Statistical analysis was done using SPSS 26, the chi-square test, with significance at p < 0.05. Results: Among the 120 participants, 84 (70%) had androgenetic alopecia. A significant association was observed between smoking status and the presence of AGA (p < 0.0001). Furthermore, the severity of AGA was significantly higher among current smokers compared to non-smokers (p = 0.017). Conclusion: There is a substantial correlation between smoking and the degree and presence of androgenetic alopecia. These results underline the significance of quitting smoking at an early age and suggest that smoking may be a modifiable risk factor in the development of AGA. https://ojs.zu.edu.pk/pjmd/article/view/3837Androgenetic AlopeciaSmokingHair lossBaldness
spellingShingle Nasira Nasr
Umaima Afzal
Karishma Mushtaq
Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
Pakistan Journal of Medicine and Dentistry
Androgenetic Alopecia
Smoking
Hair loss
Baldness
title Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
title_full Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
title_fullStr Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
title_full_unstemmed Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
title_short Association Between Smoking and Androgenetic Alopecia: A Cross-Sectional Analysis of Severity and Dose-Response Relationship in Adult Males
title_sort association between smoking and androgenetic alopecia a cross sectional analysis of severity and dose response relationship in adult males
topic Androgenetic Alopecia
Smoking
Hair loss
Baldness
url https://ojs.zu.edu.pk/pjmd/article/view/3837
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