Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery
Purpose. To investigate the variations of corneal volume (CV) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and analyze the influences of biomechanical properties on the changes of refraction and CV. Methods. Ninety-seven eye...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/1713979 |
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| author | Pinghui Wei George PM Cheng Jiamei Zhang Alex LK Ng Tommy CY Chan Vishal Jhanji Yan Wang |
| author_facet | Pinghui Wei George PM Cheng Jiamei Zhang Alex LK Ng Tommy CY Chan Vishal Jhanji Yan Wang |
| author_sort | Pinghui Wei |
| collection | DOAJ |
| description | Purpose. To investigate the variations of corneal volume (CV) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and analyze the influences of biomechanical properties on the changes of refraction and CV. Methods. Ninety-seven eyes of 97 patients undergoing SMILE and FS-LASIK were included in this retrospective study. CV was measured with Scheimpflug-based corneal topography at preoperatively and at day 1, week 1, and months 1 and 3 postoperatively. CV measured within 5 mm diameter was defined as central region volume (CV5) and between 5 mm and 10 mm diameter was defined as peripheral region volume (CV5-10). An Ocular Response Analyzer (ORA) was used to assess corneal biomechanical properties including corneal hysteresis (CH) and corneal resistant factor (CRF). The reduction of study parameters (△) were calculated by subtracting the preoperative value at various time points from the postoperative values. Results. CV had significant reduction after the SMILE and FS-LASIK procedure (P<0.05). CV5 increased significantly from postoperative day 1 to month 3 (P<0.001) in SMILE, while both CV5 and CV5-10 increased significantly in FS-LASIK (P<0.001). The increase in CV5 after SMILE was 0.11 ± 0.16 mm3，which was significantly different from FS-LASIK (0.20 ± 0.13 mm3, P=0.004). In the SMILE group, △CV5 correlated with △CRF (r = 0.498, P<0.001) and △CH (r = 0.374, P=0.007). In the FS-LASIK group, △CV5 and △CRF had a significant correlation (r = 0.363, P=0.012), but not with △CH. Conclusions. Dynamic changes in corneal volume were found after SMILE and FS-LASIK surgery. The central region significantly increased after SMILE, while both central and peripheral regions increased following FS-LASIK in the early postoperative period. SMILE was associated with less change in biomechanical properties per unit of reduction in CV compared with FS-LASIK. |
| format | Article |
| id | doaj-art-8f948bb4d34f42c1bb93ce72ab28701d |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-8f948bb4d34f42c1bb93ce72ab28701d2025-02-03T06:04:38ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/17139791713979Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK SurgeryPinghui Wei0George PM Cheng1Jiamei Zhang2Alex LK Ng3Tommy CY Chan4Vishal Jhanji5Yan Wang6Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaHong Kong Laser Eye Center, Hong Kong, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaDepartment of Ophthalmology, The University of Hong Kong, Hong Kong, ChinaDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, ChinaUPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaPurpose. To investigate the variations of corneal volume (CV) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and analyze the influences of biomechanical properties on the changes of refraction and CV. Methods. Ninety-seven eyes of 97 patients undergoing SMILE and FS-LASIK were included in this retrospective study. CV was measured with Scheimpflug-based corneal topography at preoperatively and at day 1, week 1, and months 1 and 3 postoperatively. CV measured within 5 mm diameter was defined as central region volume (CV5) and between 5 mm and 10 mm diameter was defined as peripheral region volume (CV5-10). An Ocular Response Analyzer (ORA) was used to assess corneal biomechanical properties including corneal hysteresis (CH) and corneal resistant factor (CRF). The reduction of study parameters (△) were calculated by subtracting the preoperative value at various time points from the postoperative values. Results. CV had significant reduction after the SMILE and FS-LASIK procedure (P<0.05). CV5 increased significantly from postoperative day 1 to month 3 (P<0.001) in SMILE, while both CV5 and CV5-10 increased significantly in FS-LASIK (P<0.001). The increase in CV5 after SMILE was 0.11 ± 0.16 mm3，which was significantly different from FS-LASIK (0.20 ± 0.13 mm3, P=0.004). In the SMILE group, △CV5 correlated with △CRF (r = 0.498, P<0.001) and △CH (r = 0.374, P=0.007). In the FS-LASIK group, △CV5 and △CRF had a significant correlation (r = 0.363, P=0.012), but not with △CH. Conclusions. Dynamic changes in corneal volume were found after SMILE and FS-LASIK surgery. The central region significantly increased after SMILE, while both central and peripheral regions increased following FS-LASIK in the early postoperative period. SMILE was associated with less change in biomechanical properties per unit of reduction in CV compared with FS-LASIK.http://dx.doi.org/10.1155/2020/1713979 |
| spellingShingle | Pinghui Wei George PM Cheng Jiamei Zhang Alex LK Ng Tommy CY Chan Vishal Jhanji Yan Wang Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery Journal of Ophthalmology |
| title | Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery |
| title_full | Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery |
| title_fullStr | Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery |
| title_full_unstemmed | Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery |
| title_short | Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery |
| title_sort | changes in corneal volume at different areas and its correlation with corneal biomechanics after smile and fs lasik surgery |
| url | http://dx.doi.org/10.1155/2020/1713979 |
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