An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia
Helicobacter pylori is a micro-aerophilic, slow-growing, Gram-negative spiral bacterium that colonizes the mucous lining of the human stomach. Infection with this bacterium has been identified as a cause of gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue lymphoma. Glob...
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The Journal of Infection in Developing Countries
2015-08-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/5842 |
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| author | Ali M Somily Muhammad Morshed |
| author_facet | Ali M Somily Muhammad Morshed |
| author_sort | Ali M Somily |
| collection | DOAJ |
| description | Helicobacter pylori is a micro-aerophilic, slow-growing, Gram-negative spiral bacterium that colonizes the mucous lining of the human stomach. Infection with this bacterium has been identified as a cause of gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue lymphoma. Globally, the prevalence of H. pylori-related infection is high compared to any other infectious diseases, and the rate of prevalence much higher in developing countries than in developed nations.
This review article aims to describe the trend of H. pylori-related works in the Kingdom of Saudi Arabia (KSA) and the use of various laboratory tests for the diagnosis of H. pylori-related infections in adults and children.
Therefore, published literature was referenced in the explanation and discussion of the different methods used to diagnose H. pylori-related disease, including papers published in the KSA and other Middle Eastern countries. The PubMed (http://www.ncbi.nlm.nih.gov/pubmed?cmd=search) search engine was used extensively.
Culture and histopathology tests have been employed widely to detect this pathogen at the early stage. However, over the years, an array of tests including the rapid urease test, serology, the urea breath test, the fecal antigen test, and molecular testing have been developed to diagnose and better manage H. pylori-associated diseases since the discovery of this novel pathogen.
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| format | Article |
| id | doaj-art-8f9133caa0ee4c9c92acad0c8f7c8279 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2015-08-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-8f9133caa0ee4c9c92acad0c8f7c82792025-08-20T02:27:15ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-08-0190810.3855/jidc.5842An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi ArabiaAli M Somily0Muhammad Morshed1College of Medicine, King Khalid and King Saud University Hospital, Riyadh Saudi ArabiaBCCDC Public Health Microbiology and Reference Laboratory, Provincial Health Services Authority, Vancouver, British Columbia, CanadaHelicobacter pylori is a micro-aerophilic, slow-growing, Gram-negative spiral bacterium that colonizes the mucous lining of the human stomach. Infection with this bacterium has been identified as a cause of gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue lymphoma. Globally, the prevalence of H. pylori-related infection is high compared to any other infectious diseases, and the rate of prevalence much higher in developing countries than in developed nations. This review article aims to describe the trend of H. pylori-related works in the Kingdom of Saudi Arabia (KSA) and the use of various laboratory tests for the diagnosis of H. pylori-related infections in adults and children. Therefore, published literature was referenced in the explanation and discussion of the different methods used to diagnose H. pylori-related disease, including papers published in the KSA and other Middle Eastern countries. The PubMed (http://www.ncbi.nlm.nih.gov/pubmed?cmd=search) search engine was used extensively. Culture and histopathology tests have been employed widely to detect this pathogen at the early stage. However, over the years, an array of tests including the rapid urease test, serology, the urea breath test, the fecal antigen test, and molecular testing have been developed to diagnose and better manage H. pylori-associated diseases since the discovery of this novel pathogen. https://jidc.org/index.php/journal/article/view/5842Helicobacter pyloridiagnosisPCRcultureUrea breath Testdrug susceptibility |
| spellingShingle | Ali M Somily Muhammad Morshed An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia Journal of Infection in Developing Countries Helicobacter pylori diagnosis PCR culture Urea breath Test drug susceptibility |
| title | An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia |
| title_full | An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia |
| title_fullStr | An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia |
| title_full_unstemmed | An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia |
| title_short | An update of laboratory diagnosis of Helicobacter pylori in the Kingdom of Saudi Arabia |
| title_sort | update of laboratory diagnosis of helicobacter pylori in the kingdom of saudi arabia |
| topic | Helicobacter pylori diagnosis PCR culture Urea breath Test drug susceptibility |
| url | https://jidc.org/index.php/journal/article/view/5842 |
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