Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion
A new vitamin D analogue with a trans-fused decalin as the CD-ring system and containing a sulphur atom in the side chain has been synthesized in our research group. The obtention of this analogue is based on a recently discovered transformation of hydrindane cores into decalins through a dyotropic...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2021/6429427 |
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| _version_ | 1832560537027739648 |
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| author | Hugo Santalla Uxía Gómez-Bouzó Irene Sánchez-Sanz Yagamare Fall |
| author_facet | Hugo Santalla Uxía Gómez-Bouzó Irene Sánchez-Sanz Yagamare Fall |
| author_sort | Hugo Santalla |
| collection | DOAJ |
| description | A new vitamin D analogue with a trans-fused decalin as the CD-ring system and containing a sulphur atom in the side chain has been synthesized in our research group. The obtention of this analogue is based on a recently discovered transformation of hydrindane cores into decalins through a dyotropic ring expansion in very mild conditions. |
| format | Article |
| id | doaj-art-8f8f54404ce7483a82ac71dc61ba99d9 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-8f8f54404ce7483a82ac71dc61ba99d92025-02-03T01:27:22ZengWileyJournal of Chemistry2090-90632090-90712021-01-01202110.1155/2021/64294276429427Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring ExpansionHugo Santalla0Uxía Gómez-Bouzó1Irene Sánchez-Sanz2Yagamare Fall3Departamento de Química Orgánica, Facultad de Química and Instituto de Investigación Biomédica (IBI), University of Vigo, Campus Lagoas de Marcosende, Vigo 36310, SpainDepartamento de Química Orgánica, Facultad de Química and Instituto de Investigación Biomédica (IBI), University of Vigo, Campus Lagoas de Marcosende, Vigo 36310, SpainDepartamento de Química Orgánica, Facultad de Química and Instituto de Investigación Biomédica (IBI), University of Vigo, Campus Lagoas de Marcosende, Vigo 36310, SpainDepartamento de Química Orgánica, Facultad de Química and Instituto de Investigación Biomédica (IBI), University of Vigo, Campus Lagoas de Marcosende, Vigo 36310, SpainA new vitamin D analogue with a trans-fused decalin as the CD-ring system and containing a sulphur atom in the side chain has been synthesized in our research group. The obtention of this analogue is based on a recently discovered transformation of hydrindane cores into decalins through a dyotropic ring expansion in very mild conditions.http://dx.doi.org/10.1155/2021/6429427 |
| spellingShingle | Hugo Santalla Uxía Gómez-Bouzó Irene Sánchez-Sanz Yagamare Fall Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion Journal of Chemistry |
| title | Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion |
| title_full | Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion |
| title_fullStr | Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion |
| title_full_unstemmed | Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion |
| title_short | Synthesis of a New Type of Trans-Decalin Vitamin D Analogue through a Dyotropic Ring Expansion |
| title_sort | synthesis of a new type of trans decalin vitamin d analogue through a dyotropic ring expansion |
| url | http://dx.doi.org/10.1155/2021/6429427 |
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