Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration
Background: The application of hydroxyapatite (HA) coatings represents a powerful method for improving the biorientation of titanium dental implants and their compatibility with human tissue. The research examined the consequences of applying HA coatings on dental implant integration while investig...
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| Format: | Article |
| Language: | English |
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ziauddin University
2025-04-01
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| Series: | Pakistan Journal of Medicine and Dentistry |
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| Online Access: | https://ojs.zu.edu.pk/pjmd/article/view/3574 |
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| author | Tayyaba Rafiq Iqra Amin Atiq Ur Rehman Amna Mehwish Ikram Khurram Anwar Arsalan Ahmed Ayesha Ali Khawaja |
| author_facet | Tayyaba Rafiq Iqra Amin Atiq Ur Rehman Amna Mehwish Ikram Khurram Anwar Arsalan Ahmed Ayesha Ali Khawaja |
| author_sort | Tayyaba Rafiq |
| collection | DOAJ |
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Background: The application of hydroxyapatite (HA) coatings represents a powerful method for improving the biorientation of titanium dental implants and their compatibility with human tissue. The research examined the consequences of applying HA coatings on dental implant integration while investigating bone tissue response in the nearby area.
Methods: In this cross-sectional collaborative study conducted mainly at Baqai Medical University, Lahore Medical and Dental College and Muhammad Islam Dental College, eighty patients (BMU-EC/006-22) (average age 55.3 ± 8.7 years) participated in the assessment during the period from August 2022 to December 2023 based on a purposive sampling technique. The evaluation of implant stability, together with peri-implant bone density and inflammatory response markers, constituted the clinical measurement criteria. Professionals used both patient evaluations and imaging data to evaluate the efficiency of osseointegration. The analysis of data occurred through SPSS version 20 using one way ANOVA with p-value<0.05, statistically significant. Research findings for HA-coated versus uncoated implants derived from independent t-tests for continuous variables and chi-square tests for categorical data.
Result: The study outcomes revealed that implants coated with HA exhibited better bone attachment to implant surfaces, enhanced implant stability (p = 0.012), and decreased inflammation markers (p = 0.018). Under histological examination, there was improved contact between bone tissue and the implant surface, which proves that HA contributes to quick osseointegration.
Conclusion: The implant recipients with HA coatings experienced fewer complications and better outcomes in terms of functionality.
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| format | Article |
| id | doaj-art-8f858df5e2bb437380149030cc1ccb7c |
| institution | OA Journals |
| issn | 2313-7371 2308-2593 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | ziauddin University |
| record_format | Article |
| series | Pakistan Journal of Medicine and Dentistry |
| spelling | doaj-art-8f858df5e2bb437380149030cc1ccb7c2025-08-20T02:11:37Zengziauddin UniversityPakistan Journal of Medicine and Dentistry2313-73712308-25932025-04-0114210.36283/ziun-pjmd14-2/048Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and OsseointegrationTayyaba Rafiq0Iqra Amin1Atiq Ur Rehman2Amna Mehwish Ikram3Khurram Anwar4Arsalan Ahmed5Ayesha Ali Khawaja6College of Dentistry, Lahore Medical and Dental College, Lahore,Pakistan.Muhammad Islam Dental College ,Gujranwala, Pakistan.Institute of Dentistry (IOD) CMH Lahore Medical College, Lahore Cantt,Pakistan.Islam Medical and Dental College, Sialkot. PakistanIsra Dental College ,Isra university Hyderabad Sindh, PakistanBhitai Dental & Medical College, Mirpurkhas Sindh, Pakistan.Baqai Medical University, Karachi, Pakistan. Background: The application of hydroxyapatite (HA) coatings represents a powerful method for improving the biorientation of titanium dental implants and their compatibility with human tissue. The research examined the consequences of applying HA coatings on dental implant integration while investigating bone tissue response in the nearby area. Methods: In this cross-sectional collaborative study conducted mainly at Baqai Medical University, Lahore Medical and Dental College and Muhammad Islam Dental College, eighty patients (BMU-EC/006-22) (average age 55.3 ± 8.7 years) participated in the assessment during the period from August 2022 to December 2023 based on a purposive sampling technique. The evaluation of implant stability, together with peri-implant bone density and inflammatory response markers, constituted the clinical measurement criteria. Professionals used both patient evaluations and imaging data to evaluate the efficiency of osseointegration. The analysis of data occurred through SPSS version 20 using one way ANOVA with p-value<0.05, statistically significant. Research findings for HA-coated versus uncoated implants derived from independent t-tests for continuous variables and chi-square tests for categorical data. Result: The study outcomes revealed that implants coated with HA exhibited better bone attachment to implant surfaces, enhanced implant stability (p = 0.012), and decreased inflammation markers (p = 0.018). Under histological examination, there was improved contact between bone tissue and the implant surface, which proves that HA contributes to quick osseointegration. Conclusion: The implant recipients with HA coatings experienced fewer complications and better outcomes in terms of functionality. https://ojs.zu.edu.pk/pjmd/article/view/3574HydroxyapatitesTitaniumImplantOsseointegration BiocompatibilityDental Implant Stability |
| spellingShingle | Tayyaba Rafiq Iqra Amin Atiq Ur Rehman Amna Mehwish Ikram Khurram Anwar Arsalan Ahmed Ayesha Ali Khawaja Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration Pakistan Journal of Medicine and Dentistry Hydroxyapatites Titanium Implant Osseointegration Biocompatibility Dental Implant Stability |
| title | Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration |
| title_full | Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration |
| title_fullStr | Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration |
| title_full_unstemmed | Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration |
| title_short | Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration |
| title_sort | cross sectional evaluation of hydroxyapatite coated titanium implants insights into biocompatibility and osseointegration |
| topic | Hydroxyapatites Titanium Implant Osseointegration Biocompatibility Dental Implant Stability |
| url | https://ojs.zu.edu.pk/pjmd/article/view/3574 |
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