Interpretable single-cell factor decomposition using sciRED
Abstract Single-cell RNA sequencing maps gene expression heterogeneity within a tissue. However, identifying biological signals in this data is challenging due to confounding technical factors, sparsity, and high dimensionality. Data factorization methods address this by separating and identifying s...
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| Main Authors: | Delaram Pouyabahar, Tallulah Andrews, Gary D. Bader |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57157-2 |
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