Fractional Flow Reserve following Percutaneous Coronary Intervention
Fractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to restenosis and the need for repeat revascularization...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2020/7467943 |
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| author | Udit Thakur Nancy Khav Andrea Comella Michael Michail Abdul R. Ihdayhid Eric Poon Stephen J. Nicholls Brian Ko Adam J. Brown |
| author_facet | Udit Thakur Nancy Khav Andrea Comella Michael Michail Abdul R. Ihdayhid Eric Poon Stephen J. Nicholls Brian Ko Adam J. Brown |
| author_sort | Udit Thakur |
| collection | DOAJ |
| description | Fractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to restenosis and the need for repeat revascularization. Post-PCI FFR is associated with the presence and severity of stent under-expansion and may help identify peri-stent-related complications. FFR pullback may also unmask other functionally significant lesions within the target vessel that were not appreciable on angiography. Recent studies have confirmed the prognostic utility of performing routine post-PCI FFR and suggest possible interventional targets that would improve stent durability. In this review, we detail the theoretical basis underlying post-PCI FFR, provide practical tips to facilitate measurement, and discuss the growing evidence supporting its use. |
| format | Article |
| id | doaj-art-8f80922191ef4d709a4309cb46e3a376 |
| institution | Kabale University |
| issn | 0896-4327 1540-8183 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj-art-8f80922191ef4d709a4309cb46e3a3762025-08-20T03:37:01ZengWileyJournal of Interventional Cardiology0896-43271540-81832020-01-01202010.1155/2020/74679437467943Fractional Flow Reserve following Percutaneous Coronary InterventionUdit Thakur0Nancy Khav1Andrea Comella2Michael Michail3Abdul R. Ihdayhid4Eric Poon5Stephen J. Nicholls6Brian Ko7Adam J. Brown8Monash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaDepartment of Mechanical Engineering, The University of Melbourne, Parkville, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaMonash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, VIC, AustraliaFractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to restenosis and the need for repeat revascularization. Post-PCI FFR is associated with the presence and severity of stent under-expansion and may help identify peri-stent-related complications. FFR pullback may also unmask other functionally significant lesions within the target vessel that were not appreciable on angiography. Recent studies have confirmed the prognostic utility of performing routine post-PCI FFR and suggest possible interventional targets that would improve stent durability. In this review, we detail the theoretical basis underlying post-PCI FFR, provide practical tips to facilitate measurement, and discuss the growing evidence supporting its use.http://dx.doi.org/10.1155/2020/7467943 |
| spellingShingle | Udit Thakur Nancy Khav Andrea Comella Michael Michail Abdul R. Ihdayhid Eric Poon Stephen J. Nicholls Brian Ko Adam J. Brown Fractional Flow Reserve following Percutaneous Coronary Intervention Journal of Interventional Cardiology |
| title | Fractional Flow Reserve following Percutaneous Coronary Intervention |
| title_full | Fractional Flow Reserve following Percutaneous Coronary Intervention |
| title_fullStr | Fractional Flow Reserve following Percutaneous Coronary Intervention |
| title_full_unstemmed | Fractional Flow Reserve following Percutaneous Coronary Intervention |
| title_short | Fractional Flow Reserve following Percutaneous Coronary Intervention |
| title_sort | fractional flow reserve following percutaneous coronary intervention |
| url | http://dx.doi.org/10.1155/2020/7467943 |
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