Role of microRNAs in breast cancer development and their potential as biomarkers
Breast cancer is the 2nd most common malignant disease after lung cancer; about 1 in 8 women will develop breast cancer in her lifetime. Cancer progression is a serious complication of the disease that encourages comprehensive investigation of molecular mechanisms underlying breast cancer developmen...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2018-10-01
|
| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/605 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849303250300305408 |
|---|---|
| author | K. A. Grishina V. A. Khaylenko D. V. Khaylenko A. V. Karpukhin |
| author_facet | K. A. Grishina V. A. Khaylenko D. V. Khaylenko A. V. Karpukhin |
| author_sort | K. A. Grishina |
| collection | DOAJ |
| description | Breast cancer is the 2nd most common malignant disease after lung cancer; about 1 in 8 women will develop breast cancer in her lifetime. Cancer progression is a serious complication of the disease that encourages comprehensive investigation of molecular mechanisms underlying breast cancer development. This is also important for healthcare professionals involved in patient management, since they have to choose an optimal treatment regimen. This article discusses the role of microRNAs in the development of breast cancer, their biogenesis, classification, association with various molecular subtypes of breast cancer, and their potential role in the development of new targeted drugs for breast cancer therapy. Current research on the role of microRNAs in breast cancer progression is focused on the development of markers for breast cancer prognosis, diagnostic markers and new targeted drugs. |
| format | Article |
| id | doaj-art-8f7c84399b4142f8bc694790244149d5 |
| institution | Kabale University |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj-art-8f7c84399b4142f8bc694790244149d52025-08-20T04:00:02ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272018-10-01143404710.17650/1994-4098-2018-14-3-40-47585Role of microRNAs in breast cancer development and their potential as biomarkersK. A. Grishina0V. A. Khaylenko1D. V. Khaylenko2A. V. Karpukhin3Research Center for Medical GeneticsN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; N.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; N.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaResearch Center for Medical GeneticsBreast cancer is the 2nd most common malignant disease after lung cancer; about 1 in 8 women will develop breast cancer in her lifetime. Cancer progression is a serious complication of the disease that encourages comprehensive investigation of molecular mechanisms underlying breast cancer development. This is also important for healthcare professionals involved in patient management, since they have to choose an optimal treatment regimen. This article discusses the role of microRNAs in the development of breast cancer, their biogenesis, classification, association with various molecular subtypes of breast cancer, and their potential role in the development of new targeted drugs for breast cancer therapy. Current research on the role of microRNAs in breast cancer progression is focused on the development of markers for breast cancer prognosis, diagnostic markers and new targeted drugs.https://ojrs.abvpress.ru/ojrs/article/view/605breast cancerprogressionmicrornasmarkers |
| spellingShingle | K. A. Grishina V. A. Khaylenko D. V. Khaylenko A. V. Karpukhin Role of microRNAs in breast cancer development and their potential as biomarkers Опухоли женской репродуктивной системы breast cancer progression micrornas markers |
| title | Role of microRNAs in breast cancer development and their potential as biomarkers |
| title_full | Role of microRNAs in breast cancer development and their potential as biomarkers |
| title_fullStr | Role of microRNAs in breast cancer development and their potential as biomarkers |
| title_full_unstemmed | Role of microRNAs in breast cancer development and their potential as biomarkers |
| title_short | Role of microRNAs in breast cancer development and their potential as biomarkers |
| title_sort | role of micrornas in breast cancer development and their potential as biomarkers |
| topic | breast cancer progression micrornas markers |
| url | https://ojrs.abvpress.ru/ojrs/article/view/605 |
| work_keys_str_mv | AT kagrishina roleofmicrornasinbreastcancerdevelopmentandtheirpotentialasbiomarkers AT vakhaylenko roleofmicrornasinbreastcancerdevelopmentandtheirpotentialasbiomarkers AT dvkhaylenko roleofmicrornasinbreastcancerdevelopmentandtheirpotentialasbiomarkers AT avkarpukhin roleofmicrornasinbreastcancerdevelopmentandtheirpotentialasbiomarkers |