ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER
Sinusoidal cells play the key role at all kinds of liver regeneration (physiological, reparative, fibrogenetic), which vector depends on adaptative reserves of these cells (first of all Ito cells) stressful damaging factors affect. It was demonstrated that under reparative liver regeneration the rec...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2010-06-01
|
| Series: | Вестник трансплантологии и искусственных органов |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/295 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850023411252723712 |
|---|---|
| author | A. V. Lyundup N. A. Onishchenko M. E. Krasheninnikov M. Y. Shagidulin |
| author_facet | A. V. Lyundup N. A. Onishchenko M. E. Krasheninnikov M. Y. Shagidulin |
| author_sort | A. V. Lyundup |
| collection | DOAJ |
| description | Sinusoidal cells play the key role at all kinds of liver regeneration (physiological, reparative, fibrogenetic), which vector depends on adaptative reserves of these cells (first of all Ito cells) stressful damaging factors affect. It was demonstrated that under reparative liver regeneration the recovery of hepatocytes pool originates not only from mitosis, but from regional stem cells – oval cells, Ito cells and from migrating bone marrow cells. Fibrogenetic liver regeneration occurs as a result of inhibiting stem cell function of Ito cells and bone marrow cells. |
| format | Article |
| id | doaj-art-8f69df8e2dda4268a7297a5afd73d61b |
| institution | DOAJ |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2010-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-8f69df8e2dda4268a7297a5afd73d61b2025-08-20T03:01:23ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912010-06-01121788510.15825/1995-1191-2010-1-78-85238ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVERA. V. Lyundup0N. A. Onishchenko1M. E. Krasheninnikov2M. Y. Shagidulin3Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowSinusoidal cells play the key role at all kinds of liver regeneration (physiological, reparative, fibrogenetic), which vector depends on adaptative reserves of these cells (first of all Ito cells) stressful damaging factors affect. It was demonstrated that under reparative liver regeneration the recovery of hepatocytes pool originates not only from mitosis, but from regional stem cells – oval cells, Ito cells and from migrating bone marrow cells. Fibrogenetic liver regeneration occurs as a result of inhibiting stem cell function of Ito cells and bone marrow cells.https://journal.transpl.ru/vtio/article/view/295liver regenerationito cellsbone marrow cells |
| spellingShingle | A. V. Lyundup N. A. Onishchenko M. E. Krasheninnikov M. Y. Shagidulin ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER Вестник трансплантологии и искусственных органов liver regeneration ito cells bone marrow cells |
| title | ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER |
| title_full | ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER |
| title_fullStr | ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER |
| title_full_unstemmed | ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER |
| title_short | ROLE OF LIVER SINUSOIDAL CELLS AND BONE MARROW CELLS IN REALIZATION OF REGENERATIVE STRATEGY OF NORMAL AND DAMAGED LIVER |
| title_sort | role of liver sinusoidal cells and bone marrow cells in realization of regenerative strategy of normal and damaged liver |
| topic | liver regeneration ito cells bone marrow cells |
| url | https://journal.transpl.ru/vtio/article/view/295 |
| work_keys_str_mv | AT avlyundup roleofliversinusoidalcellsandbonemarrowcellsinrealizationofregenerativestrategyofnormalanddamagedliver AT naonishchenko roleofliversinusoidalcellsandbonemarrowcellsinrealizationofregenerativestrategyofnormalanddamagedliver AT mekrasheninnikov roleofliversinusoidalcellsandbonemarrowcellsinrealizationofregenerativestrategyofnormalanddamagedliver AT myshagidulin roleofliversinusoidalcellsandbonemarrowcellsinrealizationofregenerativestrategyofnormalanddamagedliver |