Nucleos(t)ide analogs continuation is not associated with a lower risk of HBsAg seroreversion following PEG-IFN-induced HBsAg loss

Nucleos(t)ide analogs continuation is not associated with a lower risk of HBsAg seroreversion following PEG-IFN-induced HBsAg loss

Abstract Background/Aims It is unclear whether nucleos(t)ide analogs (NUCs) continuation provides clinical benefits following HBsAg seroclearance with pegylated interferon (PEG-IFN)-based therapy. This study aims to investigate the role of NUCs continuation in HBsAg seroreversion. Methods Patients w...

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Bibliographic Details
Main Authors: Na Gao, Haishi Wu, Bin Li, Huiying Yu, Lili Wu, Jing Zhang, Nan Zhang, Bingliang Lin, Qiyi Zhao, Zhiliang Gao
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Virology Journal
Subjects:
Chronic hepatitis B
Nucleos(t)ide analogs
Seroreversion
Functional cure
Online Access:https://doi.org/10.1186/s12985-025-02700-2
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