Emerging Role of Viral Infection in Periodontal Disease
Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue. In numerous instances, the local bacterial incursion and host-mediated immune reactions result in...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2025-06-01
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| Series: | Dentistry 3000 |
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| Online Access: | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/938 |
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| author | Alaa W. Izzat Batool Hassan Al-Ghurabi Lina Sami Adham Zahraa F. Shaker |
| author_facet | Alaa W. Izzat Batool Hassan Al-Ghurabi Lina Sami Adham Zahraa F. Shaker |
| author_sort | Alaa W. Izzat |
| collection | DOAJ |
| description |
Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue. In numerous instances, the local bacterial incursion and host-mediated immune reactions result in severe alveolar bone resorption. While researchers mainly concentrate on identifying periodontopathogenic bacteria, recent investigations have suggested that several viruses may also play a role in the onset and advancement of periodontitis. Human viruses can induce cytokine release from both inflammatory and non-inflammatory cells, hence compromising periodontal immune protection. This review investigates the potential role of viral infection in the pathogenesis of periodontal disease.
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| format | Article |
| id | doaj-art-8f62bc7729154ae0b847da1f94d63ede |
| institution | Kabale University |
| issn | 2167-8677 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | Dentistry 3000 |
| spelling | doaj-art-8f62bc7729154ae0b847da1f94d63ede2025-08-20T03:31:46ZengUniversity Library System, University of PittsburghDentistry 30002167-86772025-06-0113110.5195/d3000.2025.938Emerging Role of Viral Infection in Periodontal DiseaseAlaa W. IzzatBatool Hassan Al-Ghurabi0Lina Sami AdhamZahraa F. ShakerDepartment of Basic Science, College of Dentistry, University of Baghdad, Ira Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue. In numerous instances, the local bacterial incursion and host-mediated immune reactions result in severe alveolar bone resorption. While researchers mainly concentrate on identifying periodontopathogenic bacteria, recent investigations have suggested that several viruses may also play a role in the onset and advancement of periodontitis. Human viruses can induce cytokine release from both inflammatory and non-inflammatory cells, hence compromising periodontal immune protection. This review investigates the potential role of viral infection in the pathogenesis of periodontal disease. http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/938PeriodontitisHerpes VirusImmune ResponseBacteria |
| spellingShingle | Alaa W. Izzat Batool Hassan Al-Ghurabi Lina Sami Adham Zahraa F. Shaker Emerging Role of Viral Infection in Periodontal Disease Dentistry 3000 Periodontitis Herpes Virus Immune Response Bacteria |
| title | Emerging Role of Viral Infection in Periodontal Disease |
| title_full | Emerging Role of Viral Infection in Periodontal Disease |
| title_fullStr | Emerging Role of Viral Infection in Periodontal Disease |
| title_full_unstemmed | Emerging Role of Viral Infection in Periodontal Disease |
| title_short | Emerging Role of Viral Infection in Periodontal Disease |
| title_sort | emerging role of viral infection in periodontal disease |
| topic | Periodontitis Herpes Virus Immune Response Bacteria |
| url | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/938 |
| work_keys_str_mv | AT alaawizzat emergingroleofviralinfectioninperiodontaldisease AT batoolhassanalghurabi emergingroleofviralinfectioninperiodontaldisease AT linasamiadham emergingroleofviralinfectioninperiodontaldisease AT zahraafshaker emergingroleofviralinfectioninperiodontaldisease |