Emerging Role of Viral Infection in Periodontal Disease
Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue. In numerous instances, the local bacterial incursion and host-mediated immune reactions result in...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University Library System, University of Pittsburgh
2025-06-01
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| Series: | Dentistry 3000 |
| Subjects: | |
| Online Access: | http://dentistry3000.pitt.edu/ojs/dentistry3000/article/view/938 |
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| Summary: | Periodontal disease is primarily linked to a bacterial infection, such as dental plaque, which harbors a broad microbial community and can induce numerous inflammatory responses in periodontal tissue. In numerous instances, the local bacterial incursion and host-mediated immune reactions result in severe alveolar bone resorption. While researchers mainly concentrate on identifying periodontopathogenic bacteria, recent investigations have suggested that several viruses may also play a role in the onset and advancement of periodontitis. Human viruses can induce cytokine release from both inflammatory and non-inflammatory cells, hence compromising periodontal immune protection. This review investigates the potential role of viral infection in the pathogenesis of periodontal disease.
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| ISSN: | 2167-8677 |