Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition
Early nutritional support holds paramount importance for postoperative gastric cancer (GC) patients. Peptidase M20 domain containing 1 (PM20D1) is a secretory enzyme associated with glucose and lipid metabolism. However, there is a dearth of clinical studies delving into the connection between PM20D...
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-02-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2024-1111 |
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| _version_ | 1823860509137436672 |
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| author | Jin Zhengyu Chen Yuning |
| author_facet | Jin Zhengyu Chen Yuning |
| author_sort | Jin Zhengyu |
| collection | DOAJ |
| description | Early nutritional support holds paramount importance for postoperative gastric cancer (GC) patients. Peptidase M20 domain containing 1 (PM20D1) is a secretory enzyme associated with glucose and lipid metabolism. However, there is a dearth of clinical studies delving into the connection between PM20D1, lipid metabolism, and inflammatory factors in GC patients who have received enteral nutrition (EN). This research aimed to investigate the serum levels of PM20D1 in GC patients following early EN and their potential associations with lipid metabolism, nutritional markers, and inflammatory factors. |
| format | Article |
| id | doaj-art-8f5da451da134bacb152913127f0301c |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-8f5da451da134bacb152913127f0301c2025-02-10T13:24:39ZengDe GruyterOpen Medicine2391-54632025-02-012012394910.1515/med-2024-1111Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutritionJin Zhengyu0Chen Yuning1Department of General Surgery, Suzhou Dushu Lake Hospital, Suzhou, 215000, Jiangsu, P. R. ChinaDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Soochow University, No. 185, Juqian Street, Tianning District, Changzhou, 213000, Jiangsu, P. R. ChinaEarly nutritional support holds paramount importance for postoperative gastric cancer (GC) patients. Peptidase M20 domain containing 1 (PM20D1) is a secretory enzyme associated with glucose and lipid metabolism. However, there is a dearth of clinical studies delving into the connection between PM20D1, lipid metabolism, and inflammatory factors in GC patients who have received enteral nutrition (EN). This research aimed to investigate the serum levels of PM20D1 in GC patients following early EN and their potential associations with lipid metabolism, nutritional markers, and inflammatory factors.https://doi.org/10.1515/med-2024-1111pm20d1gastric cancerenteral nutritioninflammatory factorsprognosis |
| spellingShingle | Jin Zhengyu Chen Yuning Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition Open Medicine pm20d1 gastric cancer enteral nutrition inflammatory factors prognosis |
| title | Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| title_full | Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| title_fullStr | Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| title_full_unstemmed | Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| title_short | Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| title_sort | serum pm20d1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition |
| topic | pm20d1 gastric cancer enteral nutrition inflammatory factors prognosis |
| url | https://doi.org/10.1515/med-2024-1111 |
| work_keys_str_mv | AT jinzhengyu serumpm20d1levelsareassociatedwithnutritionalstatusandinflammatoryfactorsingastriccancerpatientsundergoingearlyenteralnutrition AT chenyuning serumpm20d1levelsareassociatedwithnutritionalstatusandinflammatoryfactorsingastriccancerpatientsundergoingearlyenteralnutrition |