Lipid discovery enabled by sequence statistics and machine learning
Bacterial membranes are complex and dynamic, arising from an array of evolutionary pressures. One enzyme that alters membrane compositions through covalent lipid modification is MprF. We recently identified that Streptococcus agalactiae MprF synthesizes lysyl-phosphatidylglycerol (Lys-PG) from anion...
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| Main Authors: | Priya M Christensen, Jonathan Martin, Aparna Uppuluri, Luke R Joyce, Yahan Wei, Ziqiang Guan, Faruck Morcos, Kelli L Palmer |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2024-12-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/94929 |
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