Metabolic engineering of Streptomyces roseosporus for increased production of clinically important antibiotic daptomycin
Abstract Daptomycin (DAP), a novel cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, is clinically important for treatment of infections caused by multidrug‐resistant Gram‐positive pathogens, but the low yield hampers its large‐scale industrial production. Here, we describe a combi...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-11-01
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| Series: | Microbial Biotechnology |
| Online Access: | https://doi.org/10.1111/1751-7915.70038 |
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