LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY

Based on the literature data and our personal observations in the article discusses the types of variants of the course of nervous system caused by herpesviruses. In the description of a clinical case demonstrated a classic example of limbic encephalitis infectious etiology. The study involved 36 ch...

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Main Authors: E. V. Simonova, F. S. Kharlamova, V. F. Uchaikin, I. M. Drozdova, L. P. Semenova, A. E. Andzhel
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2015-08-01
Series:Детские инфекции (Москва)
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Online Access:https://detinf.elpub.ru/jour/article/view/25
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author E. V. Simonova
F. S. Kharlamova
V. F. Uchaikin
I. M. Drozdova
L. P. Semenova
A. E. Andzhel
author_facet E. V. Simonova
F. S. Kharlamova
V. F. Uchaikin
I. M. Drozdova
L. P. Semenova
A. E. Andzhel
author_sort E. V. Simonova
collection DOAJ
description Based on the literature data and our personal observations in the article discusses the types of variants of the course of nervous system caused by herpesviruses. In the description of a clinical case demonstrated a classic example of limbic encephalitis infectious etiology. The study involved 36 children with various neurological and infectious diseases: 19 children with the diagnosis - convulsions, 8 children with the diagnosis — epilepsy, 5 children with acute viral encephalitis, 3 children with neuropathies. It was established that in the genesis of diseases such as epilepsy, convulsive syndrome, limbic encephalitis, neuropathy peripheral nerves leading role belongs to of herpes virus infection, in which the dominant role belongs HHV-6 infection. Pathogenetically proved the impact of the virus on the receptor apparatus of glia with the disorder of the functional state of mitochondria of these cells. According to our own observations provided data that result in persistence of HHV-6 variant-in mono or in combination with other herpesviruses growing threat of epilepsy and other neurological disorders.
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publisher LLC "Diagnostics and Vaccines"
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series Детские инфекции (Москва)
spelling doaj-art-8f327820d2d345a5aae20870a024320a2025-08-20T03:15:22ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-0113461310.22627/2072-8107-2014-13-4-6-1325LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGYE. V. Simonova0F. S. Kharlamova1V. F. Uchaikin2I. M. Drozdova3L. P. Semenova4A. E. Andzhel5Russian National Research Medical University named after N.I. Pirogov, Moscow, RussiaRussian National Research Medical University named after N.I. Pirogov, Moscow, RussiaRussian National Research Medical University named after N.I. Pirogov, Moscow, RussiaMorozovsky Children’s Clinical HospitalMorozovsky Children’s Clinical HospitalMorozovsky Children’s Clinical HospitalBased on the literature data and our personal observations in the article discusses the types of variants of the course of nervous system caused by herpesviruses. In the description of a clinical case demonstrated a classic example of limbic encephalitis infectious etiology. The study involved 36 children with various neurological and infectious diseases: 19 children with the diagnosis - convulsions, 8 children with the diagnosis — epilepsy, 5 children with acute viral encephalitis, 3 children with neuropathies. It was established that in the genesis of diseases such as epilepsy, convulsive syndrome, limbic encephalitis, neuropathy peripheral nerves leading role belongs to of herpes virus infection, in which the dominant role belongs HHV-6 infection. Pathogenetically proved the impact of the virus on the receptor apparatus of glia with the disorder of the functional state of mitochondria of these cells. According to our own observations provided data that result in persistence of HHV-6 variant-in mono or in combination with other herpesviruses growing threat of epilepsy and other neurological disorders.https://detinf.elpub.ru/jour/article/view/25limbic encephalitischildrenherpesepilepsyhuman herpes virus type 6convulsions
spellingShingle E. V. Simonova
F. S. Kharlamova
V. F. Uchaikin
I. M. Drozdova
L. P. Semenova
A. E. Andzhel
LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
Детские инфекции (Москва)
limbic encephalitis
children
herpes
epilepsy
human herpes virus type 6
convulsions
title LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
title_full LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
title_fullStr LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
title_full_unstemmed LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
title_short LIMBIC ENCEPHALITIS OF HERPESVIRUS ETIOLOGY
title_sort limbic encephalitis of herpesvirus etiology
topic limbic encephalitis
children
herpes
epilepsy
human herpes virus type 6
convulsions
url https://detinf.elpub.ru/jour/article/view/25
work_keys_str_mv AT evsimonova limbicencephalitisofherpesvirusetiology
AT fskharlamova limbicencephalitisofherpesvirusetiology
AT vfuchaikin limbicencephalitisofherpesvirusetiology
AT imdrozdova limbicencephalitisofherpesvirusetiology
AT lpsemenova limbicencephalitisofherpesvirusetiology
AT aeandzhel limbicencephalitisofherpesvirusetiology