Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs

Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs

BackgroundNumerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta cells and reducing oxidative phosphorylation in insulin-responsive tissues. Given the strong genetic underpinnings of T2D,...

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Bibliographic Details
Main Authors:	Mohammed Dashti, Naser M. Ali, Hussain Alsaleh, Sumi Elsa John, Rasheeba Nizam, Thangavel Alphonse Thanaraj, Fahd Al-Mulla
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Endocrinology
Subjects:	mitochondria type 2 diabetes haplogroups mtDNA variants Arab
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1443737/full
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