PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION
This article contains analysis of current combination treatment regimens for chronic hepatitis C after liver transplantation. Antiviral therapy with long-acting interferons and ribavirin is of low efficiency and high costs. The clinical and economic benefits of interferon-free treatment regimen for...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2016-06-01
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| Series: | Вестник трансплантологии и искусственных органов |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/651 |
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| author | A. A. Sukhoruk E. V. Esaulenko |
| author_facet | A. A. Sukhoruk E. V. Esaulenko |
| author_sort | A. A. Sukhoruk |
| collection | DOAJ |
| description | This article contains analysis of current combination treatment regimens for chronic hepatitis C after liver transplantation. Antiviral therapy with long-acting interferons and ribavirin is of low efficiency and high costs. The clinical and economic benefits of interferon-free treatment regimen for patients infected with genotype 1 HCV using dasabuvir, paritaprevir boosted with ritonavir, ombitasvir (Viekira Pak) and ribavirin have been shown. Registration and introduction into clinical practice of new direct-acting antiviral drugs will significantly expand the arsenal of tools for the treatment of recurrent HCV infections, in particular in patients infected with hepatitis C virus genotypes 2 and 3. |
| format | Article |
| id | doaj-art-8f16ef2fc87641d2b9efa6255c10fa79 |
| institution | DOAJ |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2016-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-8f16ef2fc87641d2b9efa6255c10fa792025-08-20T03:01:39ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912016-06-0118216317010.15825/1995-1191-2016-2-163-170551PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATIONA. A. Sukhoruk0E. V. Esaulenko1Saint Petersburg State Pediatric Medical University, Saint PetersburgSaint Petersburg State Pediatric Medical University, Saint PetersburgThis article contains analysis of current combination treatment regimens for chronic hepatitis C after liver transplantation. Antiviral therapy with long-acting interferons and ribavirin is of low efficiency and high costs. The clinical and economic benefits of interferon-free treatment regimen for patients infected with genotype 1 HCV using dasabuvir, paritaprevir boosted with ritonavir, ombitasvir (Viekira Pak) and ribavirin have been shown. Registration and introduction into clinical practice of new direct-acting antiviral drugs will significantly expand the arsenal of tools for the treatment of recurrent HCV infections, in particular in patients infected with hepatitis C virus genotypes 2 and 3.https://journal.transpl.ru/vtio/article/view/651chronic hepatitis cliver transplantationinterferon-free regimencost-analysis |
| spellingShingle | A. A. Sukhoruk E. V. Esaulenko PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION Вестник трансплантологии и искусственных органов chronic hepatitis c liver transplantation interferon-free regimen cost-analysis |
| title | PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION |
| title_full | PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION |
| title_fullStr | PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION |
| title_full_unstemmed | PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION |
| title_short | PHARMACOECONOMIC ASSESSMENT OF USING INTERFERON-FREE REGIMENS FOR CHRONIC HEPATITIS C AFTER LIVER TRANSPLANTATION |
| title_sort | pharmacoeconomic assessment of using interferon free regimens for chronic hepatitis c after liver transplantation |
| topic | chronic hepatitis c liver transplantation interferon-free regimen cost-analysis |
| url | https://journal.transpl.ru/vtio/article/view/651 |
| work_keys_str_mv | AT aasukhoruk pharmacoeconomicassessmentofusinginterferonfreeregimensforchronichepatitiscafterlivertransplantation AT evesaulenko pharmacoeconomicassessmentofusinginterferonfreeregimensforchronichepatitiscafterlivertransplantation |