Sleep-dependent memory consolidation in young and aged brains

Young children and aged individuals are more prone to memory loss than young adults. One probable reason is insufficient sleep-dependent memory consolidation. Sleep timing and sleep-stage duration differ between children and aged individuals compared to adults. Frequent daytime napping and fragmente...

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Bibliographic Details
Main Authors: Deependra Kumar, Masashi Yanagisawa, Hiromasa Funato
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Aging Brain
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589958924000203
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Summary:Young children and aged individuals are more prone to memory loss than young adults. One probable reason is insufficient sleep-dependent memory consolidation. Sleep timing and sleep-stage duration differ between children and aged individuals compared to adults. Frequent daytime napping and fragmented sleep architecture are common in children and older individuals. Moreover, sleep-dependent oscillations that play crucial roles in long-term memory storage differ among age groups. Notably, the frontal cortex, which is important for long-term memory storage undergoes major structural changes in children and aged subjects. The similarities in sleep dynamics between children and aged subjects suggest that a deficit in sleep-dependent consolidation contributes to memory loss in both age groups.
ISSN:2589-9589