Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine

The stability constants of 1,2-bis(2,5-dimethoxybenzylidene) hydrazine (DMBH) were determined using the modified Job’s method with the addition of the UV-Vis approach using salts of copper (II) (chloride and acetate) and salts of cobalt (II) (chloride and nitrate). Copper (II) chloride with a ligand...

Full description

Saved in:
Bibliographic Details
Main Authors: Rida Fatima, Sohail Nadeem, Mohsin Javed, Shahid Iqbal, Hashem O. Alsaab, Nasser S. Awwad, Hala A. Ibrahium, Eslam B. Elkaeed, Rami M. Alzhrani, Sameer Alshehri, H. Elhosiny Ali, Ayesha Mohyuddin, Nusrat Shaheen
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2022/7689617
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849403413820866560
author Rida Fatima
Sohail Nadeem
Mohsin Javed
Shahid Iqbal
Hashem O. Alsaab
Nasser S. Awwad
Hala A. Ibrahium
Eslam B. Elkaeed
Rami M. Alzhrani
Sameer Alshehri
H. Elhosiny Ali
Ayesha Mohyuddin
Nusrat Shaheen
author_facet Rida Fatima
Sohail Nadeem
Mohsin Javed
Shahid Iqbal
Hashem O. Alsaab
Nasser S. Awwad
Hala A. Ibrahium
Eslam B. Elkaeed
Rami M. Alzhrani
Sameer Alshehri
H. Elhosiny Ali
Ayesha Mohyuddin
Nusrat Shaheen
author_sort Rida Fatima
collection DOAJ
description The stability constants of 1,2-bis(2,5-dimethoxybenzylidene) hydrazine (DMBH) were determined using the modified Job’s method with the addition of the UV-Vis approach using salts of copper (II) (chloride and acetate) and salts of cobalt (II) (chloride and nitrate). Copper (II) chloride with a ligand at 1L:2M (stoichiometric ratio) was discovered to have a higher stability constant log value (6.995) than other metal salts. The stability constant log value (5.811) for cobalt (II) nitrate at 1L:2M (stoichiometric ratio) was found to be less stable than the other stability constants evaluated. Antimicrobial properties of the ligand were tested against Entamoeba coli, Candida albicans, and Staphylococcus aureus. The ligand was found to be effective against these strains, with positive results.
format Article
id doaj-art-8ef950e47c3e4d219eed7349b69705d7
institution Kabale University
issn 1687-8779
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series International Journal of Analytical Chemistry
spelling doaj-art-8ef950e47c3e4d219eed7349b69705d72025-08-20T03:37:16ZengWileyInternational Journal of Analytical Chemistry1687-87792022-01-01202210.1155/2022/7689617Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) HydrazineRida Fatima0Sohail Nadeem1Mohsin Javed2Shahid Iqbal3Hashem O. Alsaab4Nasser S. Awwad5Hala A. Ibrahium6Eslam B. Elkaeed7Rami M. Alzhrani8Sameer Alshehri9H. Elhosiny Ali10Ayesha Mohyuddin11Nusrat Shaheen12Department of ChemistryDepartment of ChemistryDepartment of ChemistryDepartment of ChemistryDepartment of Pharmaceutics and Pharmaceutical TechnologyChemistry DepartmentBiology DepartmentDepartment of Pharmaceutical SciencesDepartment of Pharmaceutics and Industrial PharmacyDepartment of Pharmaceutics and Industrial PharmacyAdvanced Functional Materials & Optoelectronic Laboratory (AFMOL)Department of ChemistryInstitute of ChemistryThe stability constants of 1,2-bis(2,5-dimethoxybenzylidene) hydrazine (DMBH) were determined using the modified Job’s method with the addition of the UV-Vis approach using salts of copper (II) (chloride and acetate) and salts of cobalt (II) (chloride and nitrate). Copper (II) chloride with a ligand at 1L:2M (stoichiometric ratio) was discovered to have a higher stability constant log value (6.995) than other metal salts. The stability constant log value (5.811) for cobalt (II) nitrate at 1L:2M (stoichiometric ratio) was found to be less stable than the other stability constants evaluated. Antimicrobial properties of the ligand were tested against Entamoeba coli, Candida albicans, and Staphylococcus aureus. The ligand was found to be effective against these strains, with positive results.http://dx.doi.org/10.1155/2022/7689617
spellingShingle Rida Fatima
Sohail Nadeem
Mohsin Javed
Shahid Iqbal
Hashem O. Alsaab
Nasser S. Awwad
Hala A. Ibrahium
Eslam B. Elkaeed
Rami M. Alzhrani
Sameer Alshehri
H. Elhosiny Ali
Ayesha Mohyuddin
Nusrat Shaheen
Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
International Journal of Analytical Chemistry
title Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
title_full Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
title_fullStr Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
title_full_unstemmed Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
title_short Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
title_sort antimicrobial activities along with spectrophotometric assessment of stability constants of copper ii and cobalt ii with 1 2 bis 2 5 dimethoxybenzylidene hydrazine
url http://dx.doi.org/10.1155/2022/7689617
work_keys_str_mv AT ridafatima antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT sohailnadeem antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT mohsinjaved antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT shahidiqbal antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT hashemoalsaab antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT nassersawwad antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT halaaibrahium antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT eslambelkaeed antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT ramimalzhrani antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT sameeralshehri antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT helhosinyali antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT ayeshamohyuddin antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine
AT nusratshaheen antimicrobialactivitiesalongwithspectrophotometricassessmentofstabilityconstantsofcopperiiandcobaltiiwith12bis25dimethoxybenzylidenehydrazine