The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis

Background. Early diagnosis of pediatric sepsis is difficult, so it is necessary to find a reliable auxiliary diagnostic method. The purpose of the study was to assess the role of RDW in the diagnosis of pediatric sepsis. Methods. We did a case control study reviewing pediatric inpatie...

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Main Authors: Lingjun Xu, Lingfeng Yuan, Keqiang Chi, Dan Zhong, Liang Huang
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2023-12-01
Series:The Turkish Journal of Pediatrics
Subjects:
Online Access:https://turkjpediatr.org/article/view/107
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author Lingjun Xu
Lingfeng Yuan
Keqiang Chi
Dan Zhong
Liang Huang
author_facet Lingjun Xu
Lingfeng Yuan
Keqiang Chi
Dan Zhong
Liang Huang
author_sort Lingjun Xu
collection DOAJ
description Background. Early diagnosis of pediatric sepsis is difficult, so it is necessary to find a reliable auxiliary diagnostic method. The purpose of the study was to assess the role of RDW in the diagnosis of pediatric sepsis. Methods. We did a case control study reviewing pediatric inpatients (≥28 days, < 18 years old) who were diagnosed with sepsis between April 2020 and November 2022. According to the sepsis-3 and Pediatric Sequential Organ Failure Assessment (pSOFA) scoring standards, 66 septic inpatients of the pediatric intensive care unit (PICU) were included in the sepsis group and 66 non-septic inpatients of the PICU were included by using the random sampling method during the same period as the control group. Results. RDW values in the sepsis group were higher than those in the control group (P < 0.001). The cut-off value, sensitivity, specificity and area under curve of RDW for sepsis were 39.15, 0.955, 0.758 and 0.943,respectively. Conclusions. Our study confirms that RDW may have a good value on the early diagnosis of pediatric sepsis.
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series The Turkish Journal of Pediatrics
spelling doaj-art-8ef09e1011f3472a9b7ad4fa575e8b682025-08-20T02:00:50ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212023-12-0165610.24953/turkjped.2023.182The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsisLingjun Xu0Lingfeng Yuan1Keqiang Chi2Dan Zhong3Liang Huang4Nanchang University, NanchangDepartment of Function, Jiangxi Provincial Children's Hospital, Nanchang.Department of Emergency, Jiangxi Provincial Children's Hospital, Nanchang.Department of Emergency, Jiangxi Provincial Children's Hospital, Nanchang.Department of Emergency, The First Affiliated Hospital of Nanchang University, Nanchang, China. Background. Early diagnosis of pediatric sepsis is difficult, so it is necessary to find a reliable auxiliary diagnostic method. The purpose of the study was to assess the role of RDW in the diagnosis of pediatric sepsis. Methods. We did a case control study reviewing pediatric inpatients (≥28 days, < 18 years old) who were diagnosed with sepsis between April 2020 and November 2022. According to the sepsis-3 and Pediatric Sequential Organ Failure Assessment (pSOFA) scoring standards, 66 septic inpatients of the pediatric intensive care unit (PICU) were included in the sepsis group and 66 non-septic inpatients of the PICU were included by using the random sampling method during the same period as the control group. Results. RDW values in the sepsis group were higher than those in the control group (P < 0.001). The cut-off value, sensitivity, specificity and area under curve of RDW for sepsis were 39.15, 0.955, 0.758 and 0.943,respectively. Conclusions. Our study confirms that RDW may have a good value on the early diagnosis of pediatric sepsis. https://turkjpediatr.org/article/view/107diagnosispediatricred blood cell distribution width (RDW)sepsis
spellingShingle Lingjun Xu
Lingfeng Yuan
Keqiang Chi
Dan Zhong
Liang Huang
The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
The Turkish Journal of Pediatrics
diagnosis
pediatric
red blood cell distribution width (RDW)
sepsis
title The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
title_full The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
title_fullStr The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
title_full_unstemmed The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
title_short The role of red blood cell distribution width (RDW) in the diagnosis of pediatric sepsis
title_sort role of red blood cell distribution width rdw in the diagnosis of pediatric sepsis
topic diagnosis
pediatric
red blood cell distribution width (RDW)
sepsis
url https://turkjpediatr.org/article/view/107
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