Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene

To elucidate Antheraea pernyi nucleopolyhedrovirus (ApNPV) ptp-2 gene characters, ApNPV ptp-2 gene was cloned using primers based on the sequence of ApNPV PstI-C fragment and then sub-cloned into prokaryotic expression vector pQE-30 to construct recombinant plasmid pQE-ptp-2. PTP-2 protein was induc...

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Main Authors: SHI Sheng-lin, PAN Min-hui, LU Cheng
Format: Article
Language:English
Published: Zhejiang University Press 2007-03-01
Series:浙江大学学报. 农业与生命科学版
Subjects:
Online Access:https://www.academax.com/doi/10.3785/1008-9209.2007.02.0125
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author SHI Sheng-lin
PAN Min-hui
LU Cheng
author_facet SHI Sheng-lin
PAN Min-hui
LU Cheng
author_sort SHI Sheng-lin
collection DOAJ
description To elucidate Antheraea pernyi nucleopolyhedrovirus (ApNPV) ptp-2 gene characters, ApNPV ptp-2 gene was cloned using primers based on the sequence of ApNPV PstI-C fragment and then sub-cloned into prokaryotic expression vector pQE-30 to construct recombinant plasmid pQE-ptp-2. PTP-2 protein was induced expression in E. coli M15. The expression accounted for 38.7 percent of the total protein. Western blot analysis of His-tag indicated that the protein expressed was His-fused. PTP-2 polyclonal antiserum was made against His-PTP-2 protein expressed in Escherichia coli. Western blot analysis of ApNPV occlusion body (OB) revealed that PTP-2 protein was not associated with the structure of ApNPV OB.
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publisher Zhejiang University Press
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series 浙江大学学报. 农业与生命科学版
spelling doaj-art-8eef0590ae2447aeb3ace0b68f3d568f2025-08-20T03:34:20ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552007-03-013312512810.3785/1008-9209.2007.02.012510089209Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 geneSHI Sheng-linPAN Min-huiLU ChengTo elucidate Antheraea pernyi nucleopolyhedrovirus (ApNPV) ptp-2 gene characters, ApNPV ptp-2 gene was cloned using primers based on the sequence of ApNPV PstI-C fragment and then sub-cloned into prokaryotic expression vector pQE-30 to construct recombinant plasmid pQE-ptp-2. PTP-2 protein was induced expression in E. coli M15. The expression accounted for 38.7 percent of the total protein. Western blot analysis of His-tag indicated that the protein expressed was His-fused. PTP-2 polyclonal antiserum was made against His-PTP-2 protein expressed in Escherichia coli. Western blot analysis of ApNPV occlusion body (OB) revealed that PTP-2 protein was not associated with the structure of ApNPV OB.https://www.academax.com/doi/10.3785/1008-9209.2007.02.0125nucleopolyhedrovirusgene expressiongene clone<italic>Antheraea pernyi</italic><italic>ptp-2</italic> gene
spellingShingle SHI Sheng-lin
PAN Min-hui
LU Cheng
Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
浙江大学学报. 农业与生命科学版
nucleopolyhedrovirus
gene expression
gene clone
<italic>Antheraea pernyi</italic>
<italic>ptp-2</italic> gene
title Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
title_full Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
title_fullStr Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
title_full_unstemmed Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
title_short Cloning and expression of Antheraea pernyi nucleopolyhedrovirus ptp-2 gene
title_sort cloning and expression of antheraea pernyi nucleopolyhedrovirus ptp 2 gene
topic nucleopolyhedrovirus
gene expression
gene clone
<italic>Antheraea pernyi</italic>
<italic>ptp-2</italic> gene
url https://www.academax.com/doi/10.3785/1008-9209.2007.02.0125
work_keys_str_mv AT shishenglin cloningandexpressionofantheraeapernyinucleopolyhedrovirusptp2gene
AT panminhui cloningandexpressionofantheraeapernyinucleopolyhedrovirusptp2gene
AT lucheng cloningandexpressionofantheraeapernyinucleopolyhedrovirusptp2gene