Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals
Plants have been studied for the production of pharmaceutical compounds for more than two decades now. Ever since the plant-made poultry vaccine against Newcastle disease virus made a breakthrough and went all the way to obtain regulatory approval, research to use plants for expression and delivery...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/2015/936940 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832565939340574720 |
|---|---|
| author | Pit Sze Liew Mohd Hair-Bejo |
| author_facet | Pit Sze Liew Mohd Hair-Bejo |
| author_sort | Pit Sze Liew |
| collection | DOAJ |
| description | Plants have been studied for the production of pharmaceutical compounds for more than two decades now. Ever since the plant-made poultry vaccine against Newcastle disease virus made a breakthrough and went all the way to obtain regulatory approval, research to use plants for expression and delivery of vaccine proteins for animals was intensified. Indeed, in view of the high production costs of veterinary vaccines, plants represent attractive biofactories and offer many promising advantages in the production of recombinant vaccine proteins. Furthermore, the possibility of conducting immunogenicity and challenge studies in target animals has greatly exaggerated the progress. Although there are no edible plant-produced animal vaccines in the market, plant-based vaccine technology has great potentials. In this review, development, uses, and advantages of plant-based recombinant protein production in various expression platforms are discussed. In addition, examples of plant-based veterinary vaccines showing strong indication in terms of efficacy in animal disease prevention are also described. |
| format | Article |
| id | doaj-art-8eed1cda855e4994944a4373059537b8 |
| institution | Kabale University |
| issn | 1687-8639 1687-8647 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-8eed1cda855e4994944a4373059537b82025-02-03T01:06:13ZengWileyAdvances in Virology1687-86391687-86472015-01-01201510.1155/2015/936940936940Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in AnimalsPit Sze Liew0Mohd Hair-Bejo1Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, MalaysiaDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, MalaysiaPlants have been studied for the production of pharmaceutical compounds for more than two decades now. Ever since the plant-made poultry vaccine against Newcastle disease virus made a breakthrough and went all the way to obtain regulatory approval, research to use plants for expression and delivery of vaccine proteins for animals was intensified. Indeed, in view of the high production costs of veterinary vaccines, plants represent attractive biofactories and offer many promising advantages in the production of recombinant vaccine proteins. Furthermore, the possibility of conducting immunogenicity and challenge studies in target animals has greatly exaggerated the progress. Although there are no edible plant-produced animal vaccines in the market, plant-based vaccine technology has great potentials. In this review, development, uses, and advantages of plant-based recombinant protein production in various expression platforms are discussed. In addition, examples of plant-based veterinary vaccines showing strong indication in terms of efficacy in animal disease prevention are also described.http://dx.doi.org/10.1155/2015/936940 |
| spellingShingle | Pit Sze Liew Mohd Hair-Bejo Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals Advances in Virology |
| title | Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals |
| title_full | Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals |
| title_fullStr | Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals |
| title_full_unstemmed | Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals |
| title_short | Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals |
| title_sort | farming of plant based veterinary vaccines and their applications for disease prevention in animals |
| url | http://dx.doi.org/10.1155/2015/936940 |
| work_keys_str_mv | AT pitszeliew farmingofplantbasedveterinaryvaccinesandtheirapplicationsfordiseasepreventioninanimals AT mohdhairbejo farmingofplantbasedveterinaryvaccinesandtheirapplicationsfordiseasepreventioninanimals |