Genome-level selection in tumors as a universal marker of resistance to therapy
Abstract Tumor evolution is shaped by selective pressures imposed by physiological factors as the tumor naturally progresses to colonize local and distant tissues, as well as by therapy. However, the distinction between these two types of pressures and their impact on tumor evolution remain elusive,...
Saved in:
| Main Authors: | Erez Persi, Praneeth R. Sudalagunta, Yuri I. Wolf, Rafael R. Canevarolo, Mehdi Damaghi, Kenneth H. Shain, Ariosto S. Silva, Eugene V. Koonin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61709-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Universal pacemaker of genome evolution.
by: Sagi Snir, et al.
Published: (2012-01-01) -
Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape
by: Nash D. Rochman, et al.
Published: (2022-04-01) -
Novel bacteriophages containing a genome of another bacteriophage within their genomes.
by: Maud M Swanson, et al.
Published: (2012-01-01) -
Evolutionary plasticity and functional versatility of CRISPR systems.
by: Eugene V Koonin, et al.
Published: (2022-01-01) -
CRISPR in mobile genetic elements: counter-defense, inter-element competition and RNA-guided transposition
by: Eugene V. Koonin, et al.
Published: (2024-12-01)