CC180 clade dynamics do not universally explain Streptococcus pneumoniae serotype 3 persistence post-vaccine: a global comparative population genomics studyResearch in context

Summary: Background: Clonal complex 180 (CC180) is currently the major clone of serotype 3 Streptococcus pneumoniae (Spn) causing disease among children and adults worldwide. The 13-valent pneumococcal conjugate vaccine (PCV13) does not have significant efficacy against serotype 3 despite polysacch...

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Bibliographic Details
Main Authors: Sydney Stanley, Catarina Silva-Costa, Joana Gomes-Silva, Jose Melo-Cristino, Richard Malley, Mario Ramirez
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:EBioMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425002257
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