A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes.

A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes.

Bacteria contain DNA polymerase I (PolI), a single polypeptide chain consisting of ∼930 residues, possessing DNA-dependent DNA polymerase, 3'-5' proofreading and 5'-3' exonuclease (also known as flap endonuclease) activities. PolI is particularly important in the processing of Ok...

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Bibliographic Details
Main Authors: Ping Xie, Jon R Sayers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0016213&type=printable
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