Invasive Aspergillosis Associated with a Foreign Body
Invasive aspergillosis is a serious complication in immunocompromised individuals. It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy. Here, we describe a patient who presented with nonspecific fever, refractory to antimicr...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2015/875168 |
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| author | Akifuddin Syed Prashanth Panta Imran Shahid David H. Felix |
| author_facet | Akifuddin Syed Prashanth Panta Imran Shahid David H. Felix |
| author_sort | Akifuddin Syed |
| collection | DOAJ |
| description | Invasive aspergillosis is a serious complication in immunocompromised individuals. It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy. Here, we describe a patient who presented with nonspecific fever, refractory to antimicrobial agents. Though it primarily involved the nasal cavity and sinuses, it perforated into the oral cavity causing palatal changes. Surprisingly, a foreign body was found in the involved tissues that might have acted as a nidus of infection. A sufficient dose (3 mg/kg/day) of liposomal amphotericin B was initiated soon after a thorough debridement procedure and the patient survived. |
| format | Article |
| id | doaj-art-8ec88937f47e49288995be5eb8b0a35d |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-8ec88937f47e49288995be5eb8b0a35d2025-08-20T02:09:21ZengWileyCase Reports in Pathology2090-67812090-679X2015-01-01201510.1155/2015/875168875168Invasive Aspergillosis Associated with a Foreign BodyAkifuddin Syed0Prashanth Panta1Imran Shahid2David H. Felix3Princess DurruShehvar Children’s and General Hospital, Purani Haveli, Hyderabad, Telangana 500002, IndiaDepartment of Oral Medicine and Radiology, MNR Dental College and Hospital, Narsapur Road, Sangareddy, Medak District, Telangana 502294, IndiaDepartment of Oral Medicine and Radiology, MNR Dental College and Hospital, Narsapur Road, Sangareddy, Medak District, Telangana 502294, IndiaNHS Education for Scotland, Westport 102, WestPort, Edinburgh EH3 9DN, UKInvasive aspergillosis is a serious complication in immunocompromised individuals. It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy. Here, we describe a patient who presented with nonspecific fever, refractory to antimicrobial agents. Though it primarily involved the nasal cavity and sinuses, it perforated into the oral cavity causing palatal changes. Surprisingly, a foreign body was found in the involved tissues that might have acted as a nidus of infection. A sufficient dose (3 mg/kg/day) of liposomal amphotericin B was initiated soon after a thorough debridement procedure and the patient survived.http://dx.doi.org/10.1155/2015/875168 |
| spellingShingle | Akifuddin Syed Prashanth Panta Imran Shahid David H. Felix Invasive Aspergillosis Associated with a Foreign Body Case Reports in Pathology |
| title | Invasive Aspergillosis Associated with a Foreign Body |
| title_full | Invasive Aspergillosis Associated with a Foreign Body |
| title_fullStr | Invasive Aspergillosis Associated with a Foreign Body |
| title_full_unstemmed | Invasive Aspergillosis Associated with a Foreign Body |
| title_short | Invasive Aspergillosis Associated with a Foreign Body |
| title_sort | invasive aspergillosis associated with a foreign body |
| url | http://dx.doi.org/10.1155/2015/875168 |
| work_keys_str_mv | AT akifuddinsyed invasiveaspergillosisassociatedwithaforeignbody AT prashanthpanta invasiveaspergillosisassociatedwithaforeignbody AT imranshahid invasiveaspergillosisassociatedwithaforeignbody AT davidhfelix invasiveaspergillosisassociatedwithaforeignbody |