Invasive Aspergillosis Associated with a Foreign Body

Invasive aspergillosis is a serious complication in immunocompromised individuals. It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy. Here, we describe a patient who presented with nonspecific fever, refractory to antimicr...

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Bibliographic Details
Main Authors: Akifuddin Syed, Prashanth Panta, Imran Shahid, David H. Felix
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2015/875168
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Summary:Invasive aspergillosis is a serious complication in immunocompromised individuals. It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy. Here, we describe a patient who presented with nonspecific fever, refractory to antimicrobial agents. Though it primarily involved the nasal cavity and sinuses, it perforated into the oral cavity causing palatal changes. Surprisingly, a foreign body was found in the involved tissues that might have acted as a nidus of infection. A sufficient dose (3 mg/kg/day) of liposomal amphotericin B was initiated soon after a thorough debridement procedure and the patient survived.
ISSN:2090-6781
2090-679X