Analysis of human brain RNA-seq data reveals combined effects of 4 types of RNA modifications and 18 types of programmed cell death on Alzheimer’s disease

Analysis of human brain RNA-seq data reveals combined effects of 4 types of RNA modifications and 18 types of programmed cell death on Alzheimer’s disease

Abstract Background RNA modification plays a critical role in Alzheimer’s disease (AD) by modulating the expression and function of AD-related genes, thereby affecting AD occurrence and progression. Programmed cell death is closely related to neuronal death and associated with neuronal loss and cogn...

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Bibliographic Details
Main Authors:	Ke Ye, Xinyu Han, Mengjie Tian, Lulu Liu, Xu Gao, Qing Xia, Dayong Wang
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Series:	Journal of Translational Medicine
Subjects:	Alzheimer’s disease RNA modification Programmed cell death Synapse Parahippocampal gyrus Machine learning
Online Access:	https://doi.org/10.1186/s12967-025-06324-6
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