Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates
Abstract Condensation and aggregation of disordered proteins in cellular non-equilibrium environments are shaped decisively by enzymes. Enzymes called kinases phosphorylate proteins, consuming the chemical fuel ATP. Protein phosphorylation by kinases such as Casein kinase 1 delta (CK1δ) determines t...
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| Main Authors: | Emanuele Zippo, Dorothee Dormann, Thomas Speck, Lukas S. Stelzl |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59676-4 |
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