Potential of nanopore sequencing for tuberculosis diagnosis and drug resistance detection

Potential of nanopore sequencing for tuberculosis diagnosis and drug resistance detection

Abstract Objectives This study evaluates the effectiveness of nanopore sequencing for accurate detection of Mycobacterium tuberculosis pathogens and drug resistance mutations in clinical specimens. Methods A retrospective analysis of 2,421 specimens from suspected tuberculosis patients admitted to X...

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Bibliographic Details
Main Authors: Fei Ren, JinBao Ma, LiYun Dang, AiFang Li, GuoLian Zhao, Yun Qi, You Xu, Han Yang, JianYing Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium
Tuberculosis
TB
Nanopore sequencing
Drug-resistance genes
Comparative study
Online Access:https://doi.org/10.1186/s12879-024-10378-0
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