MicroRNA-7a/b protects against cardiac myocyte injury in ischemia/reperfusion by targeting poly(ADP-ribose) polymerase.

MicroRNA-7a/b protects against cardiac myocyte injury in ischemia/reperfusion by targeting poly(ADP-ribose) polymerase.

<h4>Objectives</h4>MicroRNA-7 (miR-7) is highly connected to cancerous cell proliferation and metastasis. It is also involved in myocardial ischemia-reperfusion (I/R) injury and is upregulated in cardiomyocyte under simulated I/R (SI/R). We aimed to investigate the role of miR-7 during m...

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Main Authors: Bin Li, Rui Li, Chun Zhang, Hong-jun Bian, Fu Wang, Jie Xiao, Shan-wen Liu, Wei Yi, Ming-xiang Zhang, Shuang-xi Wang, Yun Zhang, Guo-hai Su, Xiao-ping Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090096&type=printable
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