High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011

Introduction: Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. Methodology: Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovir...

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Main Authors: Shamsun Nahar, Mokibul Hassan Afrad, Noorjahan Begum, Feroz Al-Mamun, Azadul Kabir Sarker, Sumon Kumar Das, Abu SG Faruque, Mahmoud Reza Pourkarim, Mohammad Shabuddin Kabir Choudhuri, Tasnim Azim, Mustafizur Rahman
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2013-11-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/2944
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author Shamsun Nahar
Mokibul Hassan Afrad
Noorjahan Begum
Feroz Al-Mamun
Azadul Kabir Sarker
Sumon Kumar Das
Abu SG Faruque
Mahmoud Reza Pourkarim
Mohammad Shabuddin Kabir Choudhuri
Tasnim Azim
Mustafizur Rahman
author_facet Shamsun Nahar
Mokibul Hassan Afrad
Noorjahan Begum
Feroz Al-Mamun
Azadul Kabir Sarker
Sumon Kumar Das
Abu SG Faruque
Mahmoud Reza Pourkarim
Mohammad Shabuddin Kabir Choudhuri
Tasnim Azim
Mustafizur Rahman
author_sort Shamsun Nahar
collection DOAJ
description Introduction: Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. Methodology: Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time RT-PCR assay with norovirus type specific primers and probes. Results: Of the 257 stool specimens tested, 28.4 % were norovirus positive. GII (71.2%) was the predominant strain followed by GI (20.5%), GI+GII (6.8%) and GIV (1.4%). Half of the norovirus positive stools (n=37) were co-infected with other pathogens. Conclusion: Continued surveillance of norovirus together with other viral and bacterial pathogens in hospitalized gastroenteritis patients as well as in the community will further elucidate the role and burden of different pathogens in diarrheal diseases.
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publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-8ea01e075e0547d2b40966d4da110ecf2025-08-20T02:27:09ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802013-11-0171110.3855/jidc.2944High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011Shamsun Nahar0Mokibul Hassan Afrad1Noorjahan Begum2Feroz Al-Mamun3Azadul Kabir Sarker4Sumon Kumar Das5Abu SG Faruque6Mahmoud Reza Pourkarim7Mohammad Shabuddin Kabir Choudhuri8Tasnim Azim9Mustafizur Rahman10Jahangirnagar University, Savar, Dhaka, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshLaboratory of Clinical and Epidemiological Virology, Rega Institute for Medical Research, University of Leuven, Leuven, BelgiumJahangirnagar University, Savar, Dhaka, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshVirology Laboratory, icddr,b, Mohakhali, Dhaka-1212, BangladeshIntroduction: Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified. Methodology: Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time RT-PCR assay with norovirus type specific primers and probes. Results: Of the 257 stool specimens tested, 28.4 % were norovirus positive. GII (71.2%) was the predominant strain followed by GI (20.5%), GI+GII (6.8%) and GIV (1.4%). Half of the norovirus positive stools (n=37) were co-infected with other pathogens. Conclusion: Continued surveillance of norovirus together with other viral and bacterial pathogens in hospitalized gastroenteritis patients as well as in the community will further elucidate the role and burden of different pathogens in diarrheal diseases. https://jidc.org/index.php/journal/article/view/2944NorovirusdiarrheaBangladesh
spellingShingle Shamsun Nahar
Mokibul Hassan Afrad
Noorjahan Begum
Feroz Al-Mamun
Azadul Kabir Sarker
Sumon Kumar Das
Abu SG Faruque
Mahmoud Reza Pourkarim
Mohammad Shabuddin Kabir Choudhuri
Tasnim Azim
Mustafizur Rahman
High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
Journal of Infection in Developing Countries
Norovirus
diarrhea
Bangladesh
title High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
title_full High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
title_fullStr High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
title_full_unstemmed High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
title_short High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011
title_sort high prevalence of noroviruses among hospitalized diarrheal patients in bangladesh 2011
topic Norovirus
diarrhea
Bangladesh
url https://jidc.org/index.php/journal/article/view/2944
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