DNMT3A GENE POINT MUTATIONS DETECTION IN ACUTE MYELOID LEUKEMIA PATIENTS USING SEQUENCING TECHNIQUE

DNMT3A GENE POINT MUTATIONS DETECTION IN ACUTE MYELOID LEUKEMIA PATIENTS USING SEQUENCING TECHNIQUE

Aim: to estimate the frequency of DNMT3A gene exons 18–26 point mutations in acute myeloid leukemia (AML) patients (pts) using target automatic sequencing technique.Material and Methods. Bone marrow and peripheral blood samples were obtained from 34 AML pts aged 21 to 64, who were treated in Sverdlo...

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Bibliographic Details
Main Authors: A. V. Vinogradov, A. V. Rezaykin, A. G. Sergeev
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2015-02-01
Series:Бюллетень сибирской медицины
Subjects:
point mutation
acute myeloid leukemia
dnmt3a gene
sequencing
Online Access:https://bulletin.ssmu.ru/jour/article/view/108
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