Rho Kinase (ROCK) Inhibitors in the Treatment of Glaucoma and Glaucoma Surgery: A Systematic Review of Early to Late Phase Clinical Trials

Rho Kinase (ROCK) Inhibitors in the Treatment of Glaucoma and Glaucoma Surgery: A Systematic Review of Early to Late Phase Clinical Trials

<b>Background/Objectives</b>: Primary open-angle glaucoma (POAG) is an anterior optic neuropathy that can lead to irreversible vision loss if untreated. Prostaglandin analogues are the first-line treatment, but new drug classes, such as rho kinase (ROCK) inhibitors, are being explored. T...

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Bibliographic Details
Main Authors: Jit Kai Tan, Peng Tee Khaw, Christin Henein
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
glaucoma
primary open-angle glaucoma
ocular hypertension
rho kinase inhibitors
glaucoma filtration surgery
fibrosis
Online Access:https://www.mdpi.com/1424-8247/18/4/523
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