The T cell receptor sequence influences the likelihood of T cell memory formation

The T cell receptor sequence influences the likelihood of T cell memory formation

Summary: The amino acid sequence of the T cell receptor (TCR) varies between T cells of an individual’s immune system. Particular TCR residues nearly guarantee mucosal-associated invariant T (MAIT) and natural killer T (NKT) cell transcriptional fates. To define how the TCR sequence affects T cell f...

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Bibliographic Details
Main Authors: Kaitlyn A. Lagattuta, Ayano C. Kohlgruber, Nouran S. Abdelfattah, Aparna Nathan, Laurie Rumker, Michael E. Birnbaum, Stephen J. Elledge, Soumya Raychaudhuri
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014499
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