Evaluation of Fifteen 5,6-Dihydrotetrazolo[1,5-<i>c</i>]quinazolines Against <i>Nakaseomyces glabrata</i>: Integrating In Vitro Studies, Molecular Docking, QSAR, and In Silico Toxicity Assessments

Evaluation of Fifteen 5,6-Dihydrotetrazolo[1,5-<i>c</i>]quinazolines Against <i>Nakaseomyces glabrata</i>: Integrating In Vitro Studies, Molecular Docking, QSAR, and In Silico Toxicity Assessments

<i>Nakaseomyces glabrata</i> (<i>Candida glabrata</i>), the second most prevalent Candida pathogen globally, has emerged as a major clinical threat due to its ability to develop high-level azole resistance. In this study, two new 5,6-dihydrotetrazolo[1,5-<i>c</i>]...

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Bibliographic Details
Main Authors: Lyudmyla Antypenko, Oleksii Antypenko, Alina Fominichenko, Iryna Karnaukh, Serhii Kovalenko, Mieko Arisawa
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Fungi
Subjects:
antifungal activity
<i>Nakaseomyces glabrata</i>
5,6-dihydrotetrazolo[1,5-<i>c</i>]quinazolines
molecular docking
toxicity
QSAR
Online Access:https://www.mdpi.com/2309-608X/10/12/816
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