Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax

THE aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, whi...

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Main Authors: Erhan Tabakoglu, Senturk Ciftci, Osman Nuri Hatipoglu, Gündeniz Altıay, Tuncay Caglar
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/09511920410001713475
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author Erhan Tabakoglu
Senturk Ciftci
Osman Nuri Hatipoglu
Gündeniz Altıay
Tuncay Caglar
author_facet Erhan Tabakoglu
Senturk Ciftci
Osman Nuri Hatipoglu
Gündeniz Altıay
Tuncay Caglar
author_sort Erhan Tabakoglu
collection DOAJ
description THE aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, which is one of the lipid peroxidation markers, in a group of patients with PSP. The study was carried out with 16 patients with PSP and 24 healthy individuals. The two groups were similar to each other in terms of sex, age and smoking attitudes. Erythrocyte superoxide dismutase activity was found to be significantly lower in patients with PSP than in the control group (p<0.01). The plasma malondialdehyde levels were significantly high in patients with PSP (p<0.01). Our results suggest that oxidative stress may contribute to the pathogenesis of PSP.
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institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2004-01-01
publisher Wiley
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series Mediators of Inflammation
spelling doaj-art-8e874789544c4e3c8f1b54303defa82b2025-08-20T03:37:17ZengWileyMediators of Inflammation0962-93511466-18612004-01-0113320921010.1080/09511920410001713475Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothoraxErhan Tabakoglu0Senturk Ciftci1Osman Nuri Hatipoglu2Gündeniz Altıay3Tuncay Caglar4Department of Chest Medicine, Trakya University Medical Faculty, Edirne 22030, TurkeyDepartment of Biochemistry, Trakya University Medical Faculty, Edirne 22030, TurkeyDepartment of Chest Medicine, Trakya University Medical Faculty, Edirne 22030, TurkeyDepartment of Chest Medicine, Trakya University Medical Faculty, Edirne 22030, TurkeyDepartment of Chest Medicine, Trakya University Medical Faculty, Edirne 22030, TurkeyTHE aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, which is one of the lipid peroxidation markers, in a group of patients with PSP. The study was carried out with 16 patients with PSP and 24 healthy individuals. The two groups were similar to each other in terms of sex, age and smoking attitudes. Erythrocyte superoxide dismutase activity was found to be significantly lower in patients with PSP than in the control group (p<0.01). The plasma malondialdehyde levels were significantly high in patients with PSP (p<0.01). Our results suggest that oxidative stress may contribute to the pathogenesis of PSP.http://dx.doi.org/10.1080/09511920410001713475Superoxide dismutaseMalondialdehydePrimary spontaneous pneumothorax.
spellingShingle Erhan Tabakoglu
Senturk Ciftci
Osman Nuri Hatipoglu
Gündeniz Altıay
Tuncay Caglar
Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
Mediators of Inflammation
Superoxide dismutase
Malondialdehyde
Primary spontaneous pneumothorax.
title Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
title_full Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
title_fullStr Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
title_full_unstemmed Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
title_short Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
title_sort levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax
topic Superoxide dismutase
Malondialdehyde
Primary spontaneous pneumothorax.
url http://dx.doi.org/10.1080/09511920410001713475
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