Identification of potential drug targets for diabetic polyneuropathy through Mendelian randomization analysis

Identification of potential drug targets for diabetic polyneuropathy through Mendelian randomization analysis

Abstract Background Diabetic polyneuropathy (DPN) is a common diabetes complication with limited treatment options. We aimed to identify circulating plasma proteins as potential therapeutic targets for DPN using Mendelian Randomization (MR). Methods The protein quantitative trait loci (pQTLs) utiliz...

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Bibliographic Details
Main Authors: Xiaokun Chen, Guohua Jiang, Tianjing Zhao, Nian Sun, Shanshan Liu, Hao Guo, Canjun Zeng, Yijun Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell & Bioscience
Subjects:
Diabetic polyneuropathy
Complications-nerves
Proteomics
Mendelian randomization
Drug development
Online Access:https://doi.org/10.1186/s13578-024-01323-4
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