Diverse functionalization of Aurora-A kinase at specified surface and buried sites by native chemical modification.
The ability to obtain a homogeneous sample of protein is invaluable when studying the effect of alterations such as post-translational modifications (PTMs). Selective functionalization of a protein to investigate the effect of PTMs on its structure or activity can be achieved by chemical modificatio...
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| Main Authors: | Fiona Rowan, Meirion Richards, Marcella Widya, Richard Bayliss, Julian Blagg |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0103935 |
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