Multiple sclerosis with early childhood onset: a case report
A 2 year old boy was admitted owing to a subacute episode of ataxic gait and hearing deficit. Computerized tomography (CT) was normal and cerebrospinal fluid (CSF) analysis revealed gamma globul.ns level of 15.4% (normal 7 to 14%). There was spontaneous remission after 7 months. At 5 years of age th...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
1988-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200012&lng=en&tlng=en |
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| _version_ | 1849736416621232128 |
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| author | Maria Isabel Campos Vergani Rubens Reimão Ana Maria Camara Silva Mauro Muskat Sandro Espósito Aron Diament |
| author_facet | Maria Isabel Campos Vergani Rubens Reimão Ana Maria Camara Silva Mauro Muskat Sandro Espósito Aron Diament |
| author_sort | Maria Isabel Campos Vergani |
| collection | DOAJ |
| description | A 2 year old boy was admitted owing to a subacute episode of ataxic gait and hearing deficit. Computerized tomography (CT) was normal and cerebrospinal fluid (CSF) analysis revealed gamma globul.ns level of 15.4% (normal 7 to 14%). There was spontaneous remission after 7 months. At 5 years of age the boy incurred a second episode with predominantly right apendicular ataxia and tonic gaze deviation to the right side. CT showed a low-density lesion in the white matter adjacent to the right frontal horn. Visual and auditory evoked potentials were abnormal. CSF revealed a mild increase in gamma globulins level of 14.5% with an abnormal T lymphocyte subsets study. The combination of visual, cerebellar, brain stem and paraventricular lesions with clear remissions and exacerbations, supported by CT, CSF and evoked potentials findings suggests the diagnosis of multiple sclerosis even at this early age. |
| format | Article |
| id | doaj-art-8e7c4ae6439c4675aaae5df3db9cce9c |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 1988-06-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-8e7c4ae6439c4675aaae5df3db9cce9c2025-08-20T03:07:17ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271988-06-0146219519710.1590/S0004-282X1988000200012S0004-282X1988000200012Multiple sclerosis with early childhood onset: a case reportMaria Isabel Campos Vergani0Rubens Reimão1Ana Maria Camara Silva2Mauro Muskat3Sandro Espósito4Aron Diament5Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloA 2 year old boy was admitted owing to a subacute episode of ataxic gait and hearing deficit. Computerized tomography (CT) was normal and cerebrospinal fluid (CSF) analysis revealed gamma globul.ns level of 15.4% (normal 7 to 14%). There was spontaneous remission after 7 months. At 5 years of age the boy incurred a second episode with predominantly right apendicular ataxia and tonic gaze deviation to the right side. CT showed a low-density lesion in the white matter adjacent to the right frontal horn. Visual and auditory evoked potentials were abnormal. CSF revealed a mild increase in gamma globulins level of 14.5% with an abnormal T lymphocyte subsets study. The combination of visual, cerebellar, brain stem and paraventricular lesions with clear remissions and exacerbations, supported by CT, CSF and evoked potentials findings suggests the diagnosis of multiple sclerosis even at this early age.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200012&lng=en&tlng=en |
| spellingShingle | Maria Isabel Campos Vergani Rubens Reimão Ana Maria Camara Silva Mauro Muskat Sandro Espósito Aron Diament Multiple sclerosis with early childhood onset: a case report Arquivos de Neuro-Psiquiatria |
| title | Multiple sclerosis with early childhood onset: a case report |
| title_full | Multiple sclerosis with early childhood onset: a case report |
| title_fullStr | Multiple sclerosis with early childhood onset: a case report |
| title_full_unstemmed | Multiple sclerosis with early childhood onset: a case report |
| title_short | Multiple sclerosis with early childhood onset: a case report |
| title_sort | multiple sclerosis with early childhood onset a case report |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1988000200012&lng=en&tlng=en |
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