Sirtuin 1 expression in elderly patients with type 2 diabetes mellitus

Sirtuin 1 expression in elderly patients with type 2 diabetes mellitus

Abstract Background The sirtuin (SIRT) family has a crucial role in aging biology. SIRT1 is a NAD+-dependent deacetylase. SIRT2 is an NAD-dependent deacetylase that mediates deacetylation of alpha-tubulin. SIRT3 is a mitochondrial enzyme that regulates mitochondrial functions, including ATP synthesi...

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Bibliographic Details
Main Authors: Mohamed M. M. Hassaan, Imam M. Esmayel, Mayada M. Mousa, Samia Hussein, Ahmed K. Y. Alkolaly, Batoul A. Hegazy, Rodalia M. Makhlouf
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:Egyptian Journal of Medical Human Genetics
Online Access:https://doi.org/10.1186/s43042-025-00770-z
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