Vortex Dynamics in the Sinus of Valsalva

Patients undergoing aortic valve repair or replacement with associated alterations in stiffness characteristics often develop abnormalities in the aortic sinus vortex, which may impact aortic valve function. The correlation between altered aortic sinus vortex and aortic valve function remains poorly...

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Main Authors: Jiaxuan Fan, Elias Sundström
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Bioengineering
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Online Access:https://www.mdpi.com/2306-5354/12/3/279
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author Jiaxuan Fan
Elias Sundström
author_facet Jiaxuan Fan
Elias Sundström
author_sort Jiaxuan Fan
collection DOAJ
description Patients undergoing aortic valve repair or replacement with associated alterations in stiffness characteristics often develop abnormalities in the aortic sinus vortex, which may impact aortic valve function. The correlation between altered aortic sinus vortex and aortic valve function remains poorly understood due to the complex fluid dynamics in the aortic valve and the challenges in simulating these conditions. The opening and closure mechanism of the aortic valve is studied using fluid–structure interaction (FSI) simulations, incorporating an idealized aortic valve model. The FSI approach models both the interaction between the fluid flow and the valve’s leaflets and the dynamic response of the leaflets during pulsatile flow conditions. Differences in the hemodynamic and vortex dynamic behaviors of aortic valve leaflets with varying stiffness are analyzed. The results reveal that, during the systolic phase, the formation of the sinus vortex is closely coupled with the jet emanating from the aortic valve and the fluttering motion of the leaflets. As leaflet stiffness increases, the peak vorticity of the sinus vortex increases, and the phase space of the vortex core develops a pronounced spiral trajectory. During the diffusion phase, the vortex strength decays exponentially, and the diffusion time is longer for stiffer leaflets, indicating a longer residence time of the sinus vortex that reduces the pressure difference on the leaflet during valve closure. Changes in leaflet stiffness play a critical role in the formation and development of sinus vortices. Furthermore, the dynamic characteristics of vortices directly affect the pressure balance on both sides of the valve leaflets. This pressure difference not only determines the opening and closing processes of the valve but also significantly influences the stability and efficiency of these actions.
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spelling doaj-art-8e79b58488b44acaa1c08fdbf4b97dfe2025-08-20T03:43:15ZengMDPI AGBioengineering2306-53542025-03-0112327910.3390/bioengineering12030279Vortex Dynamics in the Sinus of ValsalvaJiaxuan Fan0Elias Sundström1Department of Engineering Mechanics, FLOW Research Center, KTH Royal Institute of Technology, 100 44 Stockholm, SwedenDepartment of Engineering Mechanics, FLOW Research Center, KTH Royal Institute of Technology, 100 44 Stockholm, SwedenPatients undergoing aortic valve repair or replacement with associated alterations in stiffness characteristics often develop abnormalities in the aortic sinus vortex, which may impact aortic valve function. The correlation between altered aortic sinus vortex and aortic valve function remains poorly understood due to the complex fluid dynamics in the aortic valve and the challenges in simulating these conditions. The opening and closure mechanism of the aortic valve is studied using fluid–structure interaction (FSI) simulations, incorporating an idealized aortic valve model. The FSI approach models both the interaction between the fluid flow and the valve’s leaflets and the dynamic response of the leaflets during pulsatile flow conditions. Differences in the hemodynamic and vortex dynamic behaviors of aortic valve leaflets with varying stiffness are analyzed. The results reveal that, during the systolic phase, the formation of the sinus vortex is closely coupled with the jet emanating from the aortic valve and the fluttering motion of the leaflets. As leaflet stiffness increases, the peak vorticity of the sinus vortex increases, and the phase space of the vortex core develops a pronounced spiral trajectory. During the diffusion phase, the vortex strength decays exponentially, and the diffusion time is longer for stiffer leaflets, indicating a longer residence time of the sinus vortex that reduces the pressure difference on the leaflet during valve closure. Changes in leaflet stiffness play a critical role in the formation and development of sinus vortices. Furthermore, the dynamic characteristics of vortices directly affect the pressure balance on both sides of the valve leaflets. This pressure difference not only determines the opening and closing processes of the valve but also significantly influences the stability and efficiency of these actions.https://www.mdpi.com/2306-5354/12/3/279aortic heart valvefluid-structure interactionsinus vortex dynamics
spellingShingle Jiaxuan Fan
Elias Sundström
Vortex Dynamics in the Sinus of Valsalva
Bioengineering
aortic heart valve
fluid-structure interaction
sinus vortex dynamics
title Vortex Dynamics in the Sinus of Valsalva
title_full Vortex Dynamics in the Sinus of Valsalva
title_fullStr Vortex Dynamics in the Sinus of Valsalva
title_full_unstemmed Vortex Dynamics in the Sinus of Valsalva
title_short Vortex Dynamics in the Sinus of Valsalva
title_sort vortex dynamics in the sinus of valsalva
topic aortic heart valve
fluid-structure interaction
sinus vortex dynamics
url https://www.mdpi.com/2306-5354/12/3/279
work_keys_str_mv AT jiaxuanfan vortexdynamicsinthesinusofvalsalva
AT eliassundstrom vortexdynamicsinthesinusofvalsalva