FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice

FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice

Abstract Early life stress (ELS) can increase vulnerability to psychiatric disorders, but also trigger resilience. FKBP51 has been associated with an increased risk for developing psychiatric disorders, specifically in interaction with ELS exposure. Here, the contribution of FKBP51 in glutamatergic...

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Main Authors: Lotte van Doeselaar, Alexandra Abromeit, Tibor Stark, Danusa Menegaz, Markus Ballmann, Shiladitya Mitra, Huanqing Yang, Ghalia Rehawi, Rosa-Eva Huettl, Joeri Bordes, Sowmya Narayan, Daniela Harbich, Jan M. Deussing, Gerhard Rammes, Michael Czisch, Janine Knauer-Arloth, Matthias Eder, Juan Pablo Lopez, Mathias V. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57952-x
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