The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment
This study aims to evaluate the change in gait spatiotemporal parameters in subjects with Parkinson’s disease (PD) before and after Automated Mechanical Peripheral Stimulation (AMPS) treatment. Thirty-five subjects with PD and 35 healthy age-matched subjects took part in this study. A dedicated medi...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2015/390512 |
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| author | Ana Kleiner Manuela Galli Maria Gaglione Daniela Hildebrand Patrizio Sale Giorgio Albertini Fabrizio Stocchi Maria Francesca De Pandis |
| author_facet | Ana Kleiner Manuela Galli Maria Gaglione Daniela Hildebrand Patrizio Sale Giorgio Albertini Fabrizio Stocchi Maria Francesca De Pandis |
| author_sort | Ana Kleiner |
| collection | DOAJ |
| description | This study aims to evaluate the change in gait spatiotemporal parameters in subjects with Parkinson’s disease (PD) before and after Automated Mechanical Peripheral Stimulation (AMPS) treatment. Thirty-five subjects with PD and 35 healthy age-matched subjects took part in this study. A dedicated medical device (Gondola) was used to administer the AMPS. All patients with PD were treated in off levodopa phase and their gait performances were evaluated by an inertial measurement system before and after the intervention. The one-way ANOVA for repeated measures was performed to assess the differences between pre- and post-AMPS and the one-way ANOVA to assess the differences between PD patients and the control group. Spearman’s correlations assessed the associations between patients with PD clinical status (H&Y) and the percentage of improvement of the gait variables after AMPS (α<0.05 for all tests). The PD group had an improvement of 14.85% in the stride length; 14.77% in the gait velocity; and 29.91% in the gait propulsion. The correlation results showed that the higher the H&Y classification, the higher the stride length percentage of improvement. The treatment based on AMPS intervention seems to induce a better performance in the gait pattern of PD patients, mainly in intermediate and advanced stages of the condition. |
| format | Article |
| id | doaj-art-8e6b65e869174f4aa282e4b0422d107a |
| institution | OA Journals |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-8e6b65e869174f4aa282e4b0422d107a2025-08-20T02:09:22ZengWileyParkinson's Disease2090-80832042-00802015-01-01201510.1155/2015/390512390512The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation TreatmentAna Kleiner0Manuela Galli1Maria Gaglione2Daniela Hildebrand3Patrizio Sale4Giorgio Albertini5Fabrizio Stocchi6Maria Francesca De Pandis7Department of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milano, Lombardia, ItalyDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milano, Lombardia, ItalySan Raffaele Cassino Hospital Tosinvest Sanitá, 03043 Roma, Lazio, ItalyUNIMED Hospital, 13500-391 Rio Claro, SP, BrazilIRCCS San Raffaele Pisana Tosinvest Sanitá, 00163 Roma, Lazio, ItalyIRCCS San Raffaele Pisana Tosinvest Sanitá, 00163 Roma, Lazio, ItalyIRCCS San Raffaele Pisana Tosinvest Sanitá, 00163 Roma, Lazio, ItalySan Raffaele Cassino Hospital Tosinvest Sanitá, 03043 Roma, Lazio, ItalyThis study aims to evaluate the change in gait spatiotemporal parameters in subjects with Parkinson’s disease (PD) before and after Automated Mechanical Peripheral Stimulation (AMPS) treatment. Thirty-five subjects with PD and 35 healthy age-matched subjects took part in this study. A dedicated medical device (Gondola) was used to administer the AMPS. All patients with PD were treated in off levodopa phase and their gait performances were evaluated by an inertial measurement system before and after the intervention. The one-way ANOVA for repeated measures was performed to assess the differences between pre- and post-AMPS and the one-way ANOVA to assess the differences between PD patients and the control group. Spearman’s correlations assessed the associations between patients with PD clinical status (H&Y) and the percentage of improvement of the gait variables after AMPS (α<0.05 for all tests). The PD group had an improvement of 14.85% in the stride length; 14.77% in the gait velocity; and 29.91% in the gait propulsion. The correlation results showed that the higher the H&Y classification, the higher the stride length percentage of improvement. The treatment based on AMPS intervention seems to induce a better performance in the gait pattern of PD patients, mainly in intermediate and advanced stages of the condition.http://dx.doi.org/10.1155/2015/390512 |
| spellingShingle | Ana Kleiner Manuela Galli Maria Gaglione Daniela Hildebrand Patrizio Sale Giorgio Albertini Fabrizio Stocchi Maria Francesca De Pandis The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment Parkinson's Disease |
| title | The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment |
| title_full | The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment |
| title_fullStr | The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment |
| title_full_unstemmed | The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment |
| title_short | The Parkinsonian Gait Spatiotemporal Parameters Quantified by a Single Inertial Sensor before and after Automated Mechanical Peripheral Stimulation Treatment |
| title_sort | parkinsonian gait spatiotemporal parameters quantified by a single inertial sensor before and after automated mechanical peripheral stimulation treatment |
| url | http://dx.doi.org/10.1155/2015/390512 |
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