A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu

Artificial and natural energy drinks are both taken for increased energy, physical stamina, and alertness, although they differ in composition. This study investigated the effects of artificial and natural energy drinks on the testicular milieu in male pubertal rats. Eighteen Wistar rats were random...

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Main Authors: Oluwakemi T. OYELOWO, Oluwapelumi I. AWOSIKA, Taiwo H. ADESINA
Format: Article
Language:English
Published: Cluj University Press 2022-12-01
Series:Studia Universitatis Babeș-Bolyai. Biologia
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Online Access:https://studiabiologia.reviste.ubbcluj.ro/index.php/studiabio/article/view/6
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author Oluwakemi T. OYELOWO
Oluwapelumi I. AWOSIKA
Taiwo H. ADESINA
author_facet Oluwakemi T. OYELOWO
Oluwapelumi I. AWOSIKA
Taiwo H. ADESINA
author_sort Oluwakemi T. OYELOWO
collection DOAJ
description Artificial and natural energy drinks are both taken for increased energy, physical stamina, and alertness, although they differ in composition. This study investigated the effects of artificial and natural energy drinks on the testicular milieu in male pubertal rats. Eighteen Wistar rats were randomly divided into 3 groups of 6 rats each and all animals had access to food ad libitum. Group 1: (control) received water only; Group 2: (artificial energy drink- AED) received AED; Group 3: (natural energy drink- NED) received NED. A dose of 1.41ml/day/150g animal was administered and this lasted for 28 days. Sperm and testicular variables, biochemical parameters, and hormonal assays were carried out. There were significant decreases in the levels of testosterone, Lactate dehydrogenase, glucose, 3β-Hydroxysteroid dehydrogenase, and 17β- Hydroxysteroid dehydrogenase activities in AED and NED groups when compared to the control group. There was a marked increment in sperm abnormalities in the NED group when compared to AED and control groups. Also, the intake of AED led to an elevated level of Glucose-6-phosphate dehydrogenase compared to the control while a significant reduction was observed in the NED group when compared to the AED group. Artificial and natural energy drinks although consumed for strength and vigor distorted epididymis and testicular integrity via alteration of the testicular metabolism, lowering sperm quality and androgenic hormones in pubertal male Wistar rats. Article history: Received: 18 August 2022; Revised: 3 December 2022; Accepted: 16 December 2022; Available online: 22 December 2022.
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spelling doaj-art-8e68a3e5975242f28f76aa8a0ae646da2025-08-20T02:40:22ZengCluj University PressStudia Universitatis Babeș-Bolyai. Biologia2065-95122022-12-01153310.24193/subbbiol.2022.2.026A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieuOluwakemi T. OYELOWO0Oluwapelumi I. AWOSIKA1Taiwo H. ADESINA2Department of Physiology, Faculty of Basic Medical Sciences, University of Lagos, Lagos, Nigeria. *Corresponding author: ooyelowo@unilag.edu.ngDepartment of Physiology, Faculty of Basic Medical Sciences, University of Lagos, Lagos, Nigeria.. Corresponding author: ooyelowo@unilag.edu.ngDepartment of Physiology, Faculty of Basic Medical Sciences, University of Lagos, Lagos, Nigeria. *Corresponding author: ooyelowo@unilag.edu.ngArtificial and natural energy drinks are both taken for increased energy, physical stamina, and alertness, although they differ in composition. This study investigated the effects of artificial and natural energy drinks on the testicular milieu in male pubertal rats. Eighteen Wistar rats were randomly divided into 3 groups of 6 rats each and all animals had access to food ad libitum. Group 1: (control) received water only; Group 2: (artificial energy drink- AED) received AED; Group 3: (natural energy drink- NED) received NED. A dose of 1.41ml/day/150g animal was administered and this lasted for 28 days. Sperm and testicular variables, biochemical parameters, and hormonal assays were carried out. There were significant decreases in the levels of testosterone, Lactate dehydrogenase, glucose, 3β-Hydroxysteroid dehydrogenase, and 17β- Hydroxysteroid dehydrogenase activities in AED and NED groups when compared to the control group. There was a marked increment in sperm abnormalities in the NED group when compared to AED and control groups. Also, the intake of AED led to an elevated level of Glucose-6-phosphate dehydrogenase compared to the control while a significant reduction was observed in the NED group when compared to the AED group. Artificial and natural energy drinks although consumed for strength and vigor distorted epididymis and testicular integrity via alteration of the testicular metabolism, lowering sperm quality and androgenic hormones in pubertal male Wistar rats. Article history: Received: 18 August 2022; Revised: 3 December 2022; Accepted: 16 December 2022; Available online: 22 December 2022.https://studiabiologia.reviste.ubbcluj.ro/index.php/studiabio/article/view/6energy drink, jaggery, sperm quality, steroidogenic enzymes, lactate dehydrogenase.
spellingShingle Oluwakemi T. OYELOWO
Oluwapelumi I. AWOSIKA
Taiwo H. ADESINA
A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
Studia Universitatis Babeș-Bolyai. Biologia
energy drink, jaggery, sperm quality, steroidogenic enzymes, lactate dehydrogenase.
title A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
title_full A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
title_fullStr A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
title_full_unstemmed A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
title_short A comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
title_sort comparative assessment of artificial and natural energy drinks in the epididymal and testicular milieu
topic energy drink, jaggery, sperm quality, steroidogenic enzymes, lactate dehydrogenase.
url https://studiabiologia.reviste.ubbcluj.ro/index.php/studiabio/article/view/6
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