Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/2853045 |
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| author | Sin-Yeang Teow Kitson Liew Syed A. Ali Alan Soo-Beng Khoo Suat-Cheng Peh |
| author_facet | Sin-Yeang Teow Kitson Liew Syed A. Ali Alan Soo-Beng Khoo Suat-Cheng Peh |
| author_sort | Sin-Yeang Teow |
| collection | DOAJ |
| description | Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus). As demonstrated by in vitro experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived from plant is believed to have profound medicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine. S. aureus infections, particularly those caused by the multidrug-resistant strains, have emerged as a global health issue and urgent action is needed. This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent. |
| format | Article |
| id | doaj-art-8e66eda71cd748729c434eb264007b6e |
| institution | OA Journals |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-8e66eda71cd748729c434eb264007b6e2025-08-20T02:09:22ZengWileyJournal of Tropical Medicine1687-96861687-96942016-01-01201610.1155/2016/28530452853045Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief ReviewSin-Yeang Teow0Kitson Liew1Syed A. Ali2Alan Soo-Beng Khoo3Suat-Cheng Peh4Sunway Institute for Healthcare Development (SIHD), Sunway University, 47500 Bandar Sunway, Selangor Darul Ehsan, MalaysiaMolecular Pathology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), 50588 Jalan Pahang, Kuala Lumpur, MalaysiaAdvanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia (USM), 13200 Kepala Batas, Pulau Pinang, MalaysiaMolecular Pathology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), 50588 Jalan Pahang, Kuala Lumpur, MalaysiaSunway Institute for Healthcare Development (SIHD), Sunway University, 47500 Bandar Sunway, Selangor Darul Ehsan, MalaysiaCurcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad range of pharmacological properties at relatively nontoxic doses. Curcumin is found to be effective against Staphylococcus aureus (S. aureus). As demonstrated by in vitro experiment, curcumin exerts even more potent effects when used in combination with various other antibacterial agents. Hence, curcumin which is a natural product derived from plant is believed to have profound medicinal benefits and could be potentially developed into a naturally derived antibiotic in the future. However, there are several noteworthy challenges in the development of curcumin as a medicine. S. aureus infections, particularly those caused by the multidrug-resistant strains, have emerged as a global health issue and urgent action is needed. This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). We also attempt to highlight the potential challenges in the effort of developing curcumin into a therapeutic antibacterial agent.http://dx.doi.org/10.1155/2016/2853045 |
| spellingShingle | Sin-Yeang Teow Kitson Liew Syed A. Ali Alan Soo-Beng Khoo Suat-Cheng Peh Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review Journal of Tropical Medicine |
| title | Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review |
| title_full | Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review |
| title_fullStr | Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review |
| title_full_unstemmed | Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review |
| title_short | Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review |
| title_sort | antibacterial action of curcumin against staphylococcus aureus a brief review |
| url | http://dx.doi.org/10.1155/2016/2853045 |
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