Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review
Respiratory muscle weakness is a major cause of morbidity and mortality in patients with neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly, ranging from milder insufficiency that may affect only sleep initially to severe insufficiency that can be life threatening. P...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/2734054 |
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| author | Athanasios Voulgaris Maria Antoniadou Michalis Agrafiotis Paschalis Steiropoulos |
| author_facet | Athanasios Voulgaris Maria Antoniadou Michalis Agrafiotis Paschalis Steiropoulos |
| author_sort | Athanasios Voulgaris |
| collection | DOAJ |
| description | Respiratory muscle weakness is a major cause of morbidity and mortality in patients with neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly, ranging from milder insufficiency that may affect only sleep initially to severe insufficiency that can be life threatening. Patients with neuromuscular diseases exhibit very often sleep-disordered breathing, which is frequently overlooked until symptoms become more severe leading to irreversible respiratory failure necessitating noninvasive ventilation (NIV) or even tracheostomy. Close monitoring of respiratory function and sleep evaluation is currently the standard of care. Early recognition of sleep disturbances and initiation of NIV can improve the quality of life and prolong survival. This review discusses the respiratory impairment during sleep in patients with NMDs, the diagnostic tools available for early recognition of sleep-disordered breathing and the therapeutic options available for overall respiratory management of patients with NMDs. |
| format | Article |
| id | doaj-art-8e62a12a355b42d98e6160cdd16867c4 |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-8e62a12a355b42d98e6160cdd16867c42025-02-03T01:24:17ZengWileyPulmonary Medicine2090-18362090-18442019-01-01201910.1155/2019/27340542734054Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative ReviewAthanasios Voulgaris0Maria Antoniadou1Michalis Agrafiotis2Paschalis Steiropoulos3MSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceRespiratory muscle weakness is a major cause of morbidity and mortality in patients with neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly, ranging from milder insufficiency that may affect only sleep initially to severe insufficiency that can be life threatening. Patients with neuromuscular diseases exhibit very often sleep-disordered breathing, which is frequently overlooked until symptoms become more severe leading to irreversible respiratory failure necessitating noninvasive ventilation (NIV) or even tracheostomy. Close monitoring of respiratory function and sleep evaluation is currently the standard of care. Early recognition of sleep disturbances and initiation of NIV can improve the quality of life and prolong survival. This review discusses the respiratory impairment during sleep in patients with NMDs, the diagnostic tools available for early recognition of sleep-disordered breathing and the therapeutic options available for overall respiratory management of patients with NMDs.http://dx.doi.org/10.1155/2019/2734054 |
| spellingShingle | Athanasios Voulgaris Maria Antoniadou Michalis Agrafiotis Paschalis Steiropoulos Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review Pulmonary Medicine |
| title | Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review |
| title_full | Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review |
| title_fullStr | Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review |
| title_full_unstemmed | Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review |
| title_short | Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review |
| title_sort | respiratory involvement in patients with neuromuscular diseases a narrative review |
| url | http://dx.doi.org/10.1155/2019/2734054 |
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