Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction
Aim. To study diagnostic and prognostic role of hyperglycemia in patients with acute phase of myocardial infarction (MI), according to five-year follow(up results. Material and methods. In total, 130 men aged 47,1±1,7 years were examined. In 75 patients, glucose level in venous blood was measured du...
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| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1586 |
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| author | I. L. Telkova R. S. Karpov |
| author_facet | I. L. Telkova R. S. Karpov |
| author_sort | I. L. Telkova |
| collection | DOAJ |
| description | Aim. To study diagnostic and prognostic role of hyperglycemia in patients with acute phase of myocardial infarction (MI), according to five-year follow(up results. Material and methods. In total, 130 men aged 47,1±1,7 years were examined. In 75 patients, glucose level in venous blood was measured during acute MI phase, one week later, and after 21-26 days. Five(year follow-up data were available for 85,3% of the participants. Results. All patients were divided into two clinical groups (cG), according to glucose level in acute MI phase: cG I (n=43) and cG II (n=32), with glucose levels of 4,74±0,85 mM/l and 8,35±2,50 mM/l, respectively (p<0,00001). Five(year death rates in cG II and cG I were 66,6% and 48,6%, respectively (x2=2,79; p>0,05). Among patients with adverse outcomes, individuals with hypoglycemia during acute MI phase were prevalent (14,3% vs 7,1% in cG I). Maximal five(year survival was associated with isoglycemia and/or mild hyperglycemia. In patients with glucose level >7 mM/l, death HR was 1,56 (CI 1,14:3,46; p<0,05). For hypoglycaemia (<3,9 mM/l), death HR was maximal - 1,74 (CI 1,14:3,46; p<0,05). Conclusion. In acute MI phase, transitory hyperglycemia was registered in 44,4% of the patients, hypoglycemia – in 11,3%, and isoglycemia – in 44,3%. Hyper- and hypoglycemia were associated with aggravated clinical course, structural and metabolic myocardial disturbances, and adverse prognosis. |
| format | Article |
| id | doaj-art-8e624f83867e4bfc8fab39cba8a35f1a |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-8e624f83867e4bfc8fab39cba8a35f1a2025-08-20T03:18:34Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-016846511303Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarctionI. L. Telkova0R. S. Karpov1Research Institute of Cardiology, Tomsk Scientific Center, Siberian Branch, Russian Academy of Medical Sciences, TomskResearch Institute of Cardiology, Tomsk Scientific Center, Siberian Branch, Russian Academy of Medical Sciences, TomskAim. To study diagnostic and prognostic role of hyperglycemia in patients with acute phase of myocardial infarction (MI), according to five-year follow(up results. Material and methods. In total, 130 men aged 47,1±1,7 years were examined. In 75 patients, glucose level in venous blood was measured during acute MI phase, one week later, and after 21-26 days. Five(year follow-up data were available for 85,3% of the participants. Results. All patients were divided into two clinical groups (cG), according to glucose level in acute MI phase: cG I (n=43) and cG II (n=32), with glucose levels of 4,74±0,85 mM/l and 8,35±2,50 mM/l, respectively (p<0,00001). Five(year death rates in cG II and cG I were 66,6% and 48,6%, respectively (x2=2,79; p>0,05). Among patients with adverse outcomes, individuals with hypoglycemia during acute MI phase were prevalent (14,3% vs 7,1% in cG I). Maximal five(year survival was associated with isoglycemia and/or mild hyperglycemia. In patients with glucose level >7 mM/l, death HR was 1,56 (CI 1,14:3,46; p<0,05). For hypoglycaemia (<3,9 mM/l), death HR was maximal - 1,74 (CI 1,14:3,46; p<0,05). Conclusion. In acute MI phase, transitory hyperglycemia was registered in 44,4% of the patients, hypoglycemia – in 11,3%, and isoglycemia – in 44,3%. Hyper- and hypoglycemia were associated with aggravated clinical course, structural and metabolic myocardial disturbances, and adverse prognosis.https://cardiovascular.elpub.ru/jour/article/view/1586myocardial infarctionhyperglycemiadiagnostic valueprognosis |
| spellingShingle | I. L. Telkova R. S. Karpov Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction Кардиоваскулярная терапия и профилактика myocardial infarction hyperglycemia diagnostic value prognosis |
| title | Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| title_full | Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| title_fullStr | Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| title_full_unstemmed | Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| title_short | Diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| title_sort | diagnostic and prognostic role of hyperglycemia in acute phase of myocardial infarction |
| topic | myocardial infarction hyperglycemia diagnostic value prognosis |
| url | https://cardiovascular.elpub.ru/jour/article/view/1586 |
| work_keys_str_mv | AT iltelkova diagnosticandprognosticroleofhyperglycemiainacutephaseofmyocardialinfarction AT rskarpov diagnosticandprognosticroleofhyperglycemiainacutephaseofmyocardialinfarction |